CAS 12087-33-6

Decitabine impurity 13

CAS: 12087-33-6

Decitabine is a drug product that is being developed for the treatment of cancer. It has been shown to inhibit the proliferation of human tumor cells in vitro and to induce apoptosis in prostate cancer cells. Decitabine is metabolized to an active form, dideoxycitidine (DDC), which binds to DNA and inhibits the enzyme DNA polymerase alpha, leading to inhibition of DNA synthesis. Impurity 13 is a by-product of the synthesis process and can be used as an analytical standard. It can also be used as a research and development impurity standard or as a pharmacopoeia impurity standard.

Formula: C₄H₆N₆O₂

Purity: Min. 95%

Molecular weight: 170.13 g/mol

Ref: 3D-ID74844

Decitabine Impurity 14

CAS: 12087-33-6

Formula: C₅H₁₁NO₃

Molecular weight: 133.15

Ref: 4Z-D-7727

Decitabine impurity 14

CAS: 12087-33-6

Decitabine impurity 14 is an impurity of decitabine. It is a stable, natural product that has been synthesized for use as an analytical standard and pharmacopoeia reference material. Decitabine impurity 14 is a white crystalline powder with a melting point of about 152°C. It is soluble in water, ethanol and ether. The chemical name for this compound is 2-amino-4,6-dihydroxypyrimidine-5-carbonitrile hydrochloride.

Formula: C₅H₁₁NO₃

Purity: Min. 95%

Molecular weight: 133.15 g/mol

Ref: 3D-ID74843