CAS 120882-22-6
:Desfuroyl Ceftiofur
Description:
Desfuroyl Ceftiofur, with the CAS number 120882-22-6, is a metabolite of the cephalosporin antibiotic ceftiofur, primarily used in veterinary medicine. It exhibits broad-spectrum antibacterial activity, particularly against Gram-negative bacteria, making it effective in treating infections in livestock. The compound is characterized by its stability and solubility in water, which facilitates its administration in injectable formulations. Desfuroyl Ceftiofur is known for its relatively low toxicity profile, contributing to its safety in veterinary applications. Its mechanism of action involves inhibiting bacterial cell wall synthesis, leading to cell lysis and death. Additionally, it is important to monitor its residues in food products, as regulatory agencies set limits to ensure consumer safety. The pharmacokinetics of Desfuroyl Ceftiofur indicate a prolonged half-life, allowing for less frequent dosing in clinical settings. Overall, its efficacy and safety profile make it a valuable tool in managing bacterial infections in animals.
Formula:C14H15N5O5S3
InChI:InChI=1/C14H15N5O5S3/c1-24-18-7(6-4-27-14(15)16-6)10(20)17-8-11(21)19-9(13(22)23)5(2-25)3-26-12(8)19/h4,8,12,25H,2-3H2,1H3,(H2,15,16)(H,17,20)(H,22,23)/b18-7+/t8-,12-/m1/s1
Synonyms:- (6R,7R)-7-[[(2Z)-(2-Amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-(mercaptomethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Aci
- (6R,7R)-7-[[(2Z)-(2-Amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-(mercaptomethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid
- (6R,7R)-7-{[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-8-oxo-3-(sulfanylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
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Found 9 products.
Desfuroyl Ceftiofur Sodium Salt
CAS:Formula:C14H14N5O5S3·NaColor and Shape:Pale Yellow SolidMolecular weight:428.48 22.99Desfuroyl Ceftiofur
CAS:<p>Desfuroyl Ceftiofur</p>Color and Shape:White To Off White PowderMolecular weight:429.49g/molDesfuroyl Ceftiofur (>85%)
CAS:Controlled Product<p>Stability Hygroscopic, Temperature Sensitive<br>Applications A metabolite of Ceftiofur (C244700), which is microbiologic active.<br>References Washburn, K., et al.: J. Vet. Pharm. Ther., 28, 247 (2005),<br></p>Formula:C14H15N5O5S3Purity:>85%Color and Shape:BeigeMolecular weight:429.49Desfuroyl Ceftiofur-d3
CAS:Controlled Product<p>Applications A metabolite of Ceftiofur (C244700), which is microbiologic active.<br>References Washburn, K., et al.: J. Vet. Pharm. Ther., 28, 247 (2005),<br></p>Formula:C14H12D3N5O5S3Purity:>85%Color and Shape:White To Light BrownMolecular weight:432.51Desfuroyl ceftiofur sodium
CAS:<p>Desfuroyl ceftiofur sodium is a veterinary cephalosporin antibiotic, which is derived from cephalosporin C, a beta-lactam antibiotic produced by the fungus Cephalosporium acremonium. Its mode of action involves the inhibition of bacterial cell wall synthesis by binding to and inactivating penicillin-binding proteins (PBPs). This prevents the cross-linking of peptidoglycan layers, leading to cell lysis and bacterial death, particularly effective against Gram-negative and some Gram-positive bacteria.</p>Formula:C14H15N5O5S3•NaPurity:Min. 95%Molecular weight:452.5 g/molDesfuroyl ceftiofur
CAS:<p>Desfuroyl ceftiofur is a β-lactam antibiotic that has a wide spectrum of activity against bacteria. It is effective for the treatment of respiratory infections, skin and soft tissue infections, and urinary tract infections. Desfuroyl ceftiofur is also used to treat mastitis in dairy cattle. The efficacy of desfuroyl ceftiofur has been demonstrated in clinical studies and in studies on laboratory animals. The bactericidal activity of desfuroyl ceftiofur can be attributed to its inhibition of the synthesis of bacterial cell wall mucopeptides, which are essential for bacterial growth. Desfuroyl ceftiofur binds to penicillin-binding proteins (PBPs) on bacterial cell walls by competitive inhibition and inhibits the formation of an antibiotic-inhibitor complex with the enzyme cell wall synthesis that is required for cell wall biosynthesis, inhibiting protein synthesis and cell division. Desfuroyl ceftiofur has</p>Formula:C14H15N5O5S3Purity:Min. 85 Area-%Color and Shape:White PowderMolecular weight:429.5 g/mol
