CAS 1209-66-1

phenothiazine S,S-dioxide

Description:

Phenothiazine S,S-dioxide, with the CAS number 1209-66-1, is a derivative of phenothiazine, a compound known for its use in pharmaceuticals, particularly as an antipsychotic and antihistamine. This compound features a sulfur atom that is oxidized to form a sulfone group, which enhances its solubility and alters its biological activity compared to its parent phenothiazine structure. Phenothiazine S,S-dioxide is characterized by its aromatic system, which contributes to its stability and reactivity. It typically appears as a solid at room temperature and is soluble in organic solvents. The presence of the sulfone group can influence its interactions with biological targets, making it of interest in medicinal chemistry. Additionally, phenothiazine derivatives are known for their potential applications in dye chemistry and as intermediates in organic synthesis. Safety data indicates that while it may pose some hazards, proper handling and storage can mitigate risks associated with its use.

Formula: C₁₂H₉NO₂S

InChI: InChI=1S/C12H9NO2S/c14-16(15)11-7-3-1-5-9(11)13-10-6-2-4-8-12(10)16/h1-8,13H

InChI key: InChIKey=ZAYUOSICZWFJSW-UHFFFAOYSA-N

SMILES: O=S1(=O)C=2C(NC=3C1=CC=CC3)=CC=CC2

Synonyms:

• 10H-5λ6-Phenothiazine-5,5-dione
• 10H-phenothiazine 5,5-dioxide
• 5,5-Dioxophenothiazine
• Phenothiazine Sulphone
• Phenothiazine, 5,5-dioxide
• Phenothiazine S,S-dioxide
• 5,5-Dioxo-10H-phenothiazine
• Phenothiazine dioxide

10H-Phenothiazine 5,5-dioxide

CAS: 1209-66-1

10H-Phenothiazine 5,5-dioxide

Purity: 95%

Molecular weight: 231.28g/mol

Ref: 54-OR1072860

10H-Phenothiazine 5,5-Dioxide

CAS: 1209-66-1

Formula: C₁₂H₉NO₂S

Purity: >95.0%(HPLC)(qNMR)

Color and Shape: White to Light yellow to Light orange powder to crystal

Molecular weight: 231.27

Ref: 3B-D6164

Phenothiazine S,S-Dioxide

CAS: 1209-66-1

Formula: C₁₂H₉NO₂S

Molecular weight: 231.27

Ref: 4Z-P-332001

Phenothiazine S,S-Dioxide

CAS: 1209-66-1

Formula: C₁₂H₉NO₂S

Molecular weight: 231.27

Ref: ST-EA-CP-P86012

Phenothiazine S,S-Dioxide

Controlled Product

CAS: 1209-66-1

Applications Phenothiazine S,S-Dioxide is a derivative of Phenothiazine (P318040), a key component of antipsychotic and antihistaminic drugs.
References Bansode, T., et al.: Eur. J. Med. Chem., 44, 5094 (2009), Baell, J., et al.: J. Med. Chem., 53, 2719 (2010), Howard, P., et al.: Environ. Sci. Technol., 44, 2277 (2010), Koren, J., et al.: J. Biol. Chem., 285, 2498 (2010), Amobi, N., et al.: Eur. J. Pharmacol., 627, 285 (2010),

Formula: C₁₂H₉NO₂S

Color and Shape: White To Off-White

Molecular weight: 231.27

Ref: TR-P297600

Phenothiazine S,S-dioxide

CAS: 1209-66-1

Phenothiazine S,S-dioxide is a fluorescent anion that can be used as a buffer. It has an absorption maximum at 514 nm in the visible region and a fluorescence emission maximum at 592 nm. Phenothiazine S,S-doxide blocks the emission of light from phosphor by absorbing the light and reemitting it at a longer wavelength. The luminescence intensity increases with increasing concentration of phenothiazine S,S-dioxide. This compound has been used to develop devices that detect anions in drinking water such as chloride ion. Phenothiazines are also known to have anti-inflammatory effects due to their ability to inhibit prostaglandin synthesis.

Formula: C₁₂H₉NO₂S

Purity: Min. 95%

Molecular weight: 231.27 g/mol

Ref: 3D-BAA20966