CAS 120912-54-1

SP-5,6-DCI-CBIMPS

Description:

SP-5,6-DCI-CBIMPS, identified by its CAS number 120912-54-1, is a chemical compound that belongs to a class of substances known for their potential applications in various fields, including medicinal chemistry and materials science. While specific characteristics such as molecular weight, solubility, and reactivity may vary, compounds of this nature often exhibit unique structural features that contribute to their biological activity or functional properties. Typically, such compounds may possess specific functional groups that influence their interaction with biological targets or their behavior in different environments. Additionally, they may demonstrate stability under certain conditions, making them suitable for research and development purposes. However, detailed information regarding its toxicity, environmental impact, and regulatory status would require further investigation, as these factors are crucial for understanding the safe handling and application of the substance in both laboratory and industrial settings. Always refer to safety data sheets and relevant literature for comprehensive information on specific chemical substances.

Formula: C₁₂H₁₀Cl₂N₂NaO₅PS

InChI: InChI=1/C12H11Cl2N2O5PS.Na/c13-5-1-7-8(2-6(5)14)16(4-15-7)12-10(17)11-9(20-12)3-19-22(18,23)21-11;/h1-2,4,9-12,17H,3H2,(H,18,23);/q;+1/p-1/t9-,10-,11-,12-,22?;/m1./s1

SMILES: c1c(c(cc2c1ncn2C1C(C2C(COP(=S)(O)O2)O1)O)Cl)Cl.[Na]

Synonyms:

• 5,6-Dichloro-1-Beta-D-Ribofuranosylbenzimidazole-3’,5’-Monophosphorothioate
• 5,6-Dichlorobenzimidazoleriboside-3’,5’-Monophosphorothioate,Sp-Isomer(Sp5,6-Dcl-Cbimps),
• Sp-5,6-Dichloro-1-Beta-D-Ribofuranosylbenzimidazole-3',5'-Monophosphorothioate
• 5,6-Dichloro-1-B-D-ribofuranosylbenzimidazole-3',5'-cyclic monophosphothioa
• 5,6-Dichloro-1-b-D-ribofuranosylbenzimidazole-3μ,5μ-cyclic monophosphorothioate, Sp- isomer sodium salt
• 5,6-Dcl-Cbimpsasp-Isomer
• sodium (4aR,6R,7R,7aS)-6-(5,6-dichloro-1H-benzimidazol-1-yl)-7-hydroxytetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-2-olate 2-sulfide

5,6-Dichloro-(1-b-D-ribofuranosyl) benzimidazole 3'',5''-cyclic monophosphothioate, Sp-isomer sodium salt

CAS: 120912-54-1

Formula: C₁₂H₁₀Cl₂N₂O₅PSNa

Molecular weight: 419.15

Ref: 7W-GN8098

5,6-Dichloro-(1-b-D-ribofuranosyl) benzimidazole 3',5'-cyclic monophosphothioate, Sp-isomer sodium salt

CAS: 120912-54-1

5,6-Dichloro-(1-b-D-ribofuranosyl) benzimidazole 3',5'-cyclic monophosphothioate, Sp-isomer sodium salt (SPP) is a cytostatic agent that binds to the α subunit of the voltage-dependent Ca2+ channel. It has been shown to inhibit tumor growth in mouse models of hyperproliferative diseases such as bladder cancer and pulmonary fibrosis. SPP also inhibits the proliferation of human bladder cells in culture by inhibiting cyclic nucleotide phosphodiesterase activity. This leads to an increase in intracellular calcium concentrations and activation of cation channels. SPP is an analog of rolipram, which has been shown to have anti-inflammatory effects on detrusor muscle cells.

Formula: C₁₂H₁₀Cl₂N₂O₅P·Na

Purity: Min. 95%

Molecular weight: 419.16 g/mol

Ref: 3D-ND08934

Sp-5,6-DCl-cBIMPS

CAS: 120912-54-1

Sp-5,6-DCl-cBIMPS activates cAMP-PK, stimulates insulin, inhibits Rho, Gq, G12/G13 in platelets.

Formula: C₁₂H₁₁Cl₂N₂O₅PS

Color and Shape: Solid

Molecular weight: 397.17

Ref: TM-T72591