CAS 1209457-55-5

Nicotinic Acid-13C6, d4 N-Hydroxysuccinimide Ester

Description:

Nicotinic Acid-13C6, d4 N-Hydroxysuccinimide Ester, identified by the CAS number 1209457-55-5, is a derivative of nicotinic acid, which is a form of vitamin B3. This compound is characterized by the incorporation of stable isotopes, specifically carbon-13 and deuterium, which are used in various analytical applications, including mass spectrometry. The presence of the N-hydroxysuccinimide (NHS) moiety enhances the reactivity of the ester, making it useful for conjugation reactions, particularly in bioconjugation and labeling studies. The NHS ester can react with amines to form stable amide bonds, facilitating the attachment of biomolecules such as proteins or peptides. The isotopic labeling allows for precise tracking and quantification in complex biological systems. Overall, this compound is valuable in research fields such as proteomics, metabolomics, and drug development, where understanding molecular interactions and dynamics is crucial. Its stability and reactivity make it a versatile tool in chemical biology and analytical chemistry.

Formula: C₁₀H₈N₂O₄

Synonyms:

• N-(3-Pyridinyloyloxy-13C6,d4)succinimide
• N-(Nicotinoyloxy-13C6,d4)succinimide
• Succinimidyl Nicotinate-13C6,d4
• 3-Pyridinecarboxylic Acid-13C6,d4 2,5-Dioxo-1-pyrrolidinyl Ester
• Nicotinic Acid-13C6, d4 N-Hydroxysuccinimide Ester

Nicotinic Acid-13C6,d4 N-Hydroxysuccinimide Ester

Controlled Product

CAS: 1209457-55-5

Applications Used for clinical pharmacokinetic studies.
References Kyte, J., et al.: J. Mol. Biol., 157, 105 (1982), Kamo, M., et al.: Eur. J. Biochem., 255, 162 (1998), Wu, C., et al.: Nat. Biotechnol., 21, 532 (2003),

Formula: C₆C₄D₄H₄N₂O₄

Color and Shape: Neat

Molecular weight: 230.162

Ref: TR-N429257