CAS 121-28-8

1-(3,4-Dihydroxyphenyl)-2-[(1-methylethyl)amino]ethanone

Description:

1-(3,4-Dihydroxyphenyl)-2-[(1-methylethyl)amino]ethanone, commonly known as acetaminophen or paracetamol, is a widely used analgesic and antipyretic agent. It is characterized by its ability to relieve pain and reduce fever, making it a common over-the-counter medication. The molecular structure features a phenolic hydroxyl group and an acetamide functional group, contributing to its pharmacological properties. Acetaminophen is generally well-tolerated, with a low incidence of gastrointestinal side effects compared to non-steroidal anti-inflammatory drugs (NSAIDs). However, it is crucial to adhere to recommended dosages, as excessive intake can lead to hepatotoxicity. The compound is soluble in water and exhibits a relatively low melting point, indicating its solid-state at room temperature. Its mechanism of action involves the inhibition of cyclooxygenase enzymes, leading to decreased production of prostaglandins, which are mediators of pain and inflammation. Overall, acetaminophen is a vital component of pain management and fever reduction in clinical practice.

Formula: C₁₁H₁₅NO₃

InChI: InChI=1S/C11H15NO3/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8/h3-5,7,12-14H,6H2,1-2H3

InChI key: InChIKey=BIQMIYWSZZTXEX-UHFFFAOYSA-N

SMILES: C(CNC(C)C)(=O)C1=CC(O)=C(O)C=C1

Synonyms:

• 1-(3,4-Dihydroxyphenyl)-2-(Propan-2-Ylamino)Ethanone
• 1-(3,4-Dihydroxyphenyl)-2-[(1-methylethyl)amino]ethanone
• 1-(3,4-Dihydroxyphenyl)-2-[(propan-2-yl)amino]ethan-1-one
• 3',4'-Dihydroxy-2-(isopropylamino)acetophenone
• 3,4-Dihydroxy-alpha-isopropylaminoacetophenone
• 3,4-Dihydroxy-α-isopropylaminoacetophenone
• 3′,4′-Dihydroxy-2-(isopropylamino)-acetophenone
• Acetophenone, 3',4'-dihydroxy-2-(isopropylamino)-
• Acetophenone, 3′,4′-dihydroxy-2-(isopropylamino)-
• Aludrone
• Brn 2105828
• Ethanone, 1-(3,4-dihydroxyphenyl)-2-((1-methylethyl)amino)-
• Ethanone, 1-(3,4-dihydroxyphenyl)-2-((1-methylethyl)amino)- (9CI)
• Isoproterenone
• N-Isopropylnoradrenalone
• Nsc 163353
• S 35179
• 1-(3,4-Dihydroxyphenyl)-2-((1-methylethyl)amino)ethan-1-one

1-(3,4-Dihydroxyphenyl)-2-[(1-methylethyl)amino]-ethanone-d7 Hydrochloride

Controlled Product

CAS: 121-28-8, 16899-81-3

Applications 1-(3,4-Dihydroxyphenyl)-2-[(1-methylethyl)amino]-ethanone-d7 Hydrochloride is labelled 1-(3,4-Dihydroxyphenyl)-2-[(1-methylethyl)amino]-ethanone Hydrochloride (D448195), an impurity of Isoprenaline (I874200, HCl salt) which is non-selective beta-adrenergic agonist. Isoprenaline is used in the treatment of bradycardia.
References Kikkawa, H. et al.: Biol. Pharmac. Bull., 17, 1047 (1994); Kral, P. et al.: Psychopharmacologia, 26, 79 (1972); Giles, R.E. et al.: J. Pharmacol. Exp. Ther., 186, 472 (1973)

Formula: C₁₁D₆H₉NO₃·HCl·D

Color and Shape: Neat

Molecular weight: 253.754

Ref: TR-D448197

Isoproterenone

CAS: 121-28-8

Formula: C₁₁H₁₅NO₃

Molecular weight: 209.25

Ref: ST-EA-CP-I7032