CAS 121-60-8

4-Acetamidobenzenesulfonyl chloride

Description:

4-Acetamidobenzenesulfonyl chloride, with the CAS number 121-60-8, is an organic compound that features both an acetamido group and a sulfonyl chloride functional group. It is typically a white to off-white solid that is soluble in organic solvents such as dichloromethane and chloroform, but is generally insoluble in water due to its hydrophobic characteristics. This compound is known for its reactivity, particularly as a sulfonyl chloride, which allows it to participate in various chemical reactions, including acylation and sulfonylation. It is often used as a reagent in organic synthesis, particularly in the preparation of sulfonamides and other derivatives. The presence of the acetamido group enhances its utility in medicinal chemistry, where it can serve as a building block for pharmaceuticals. However, it should be handled with care due to its potential to release hydrochloric acid upon hydrolysis, and it may pose health risks if inhaled or ingested. Proper safety precautions, including the use of personal protective equipment, are essential when working with this compound.

Formula: C₈H₈ClNO₃S

InChI: InChI=1S/C8H8ClNO3S/c1-6(11)10-7-2-4-8(5-3-7)14(9,12)13/h2-5H,1H3,(H,10,11)

InChI key: InChIKey=GRDXCFKBQWDAJH-UHFFFAOYSA-N

SMILES: S(Cl)(=O)(=O)C1=CC=C(NC(C)=O)C=C1

Synonyms:

• 4 Acetamido Benzene Sulfonyl Chloride
• 4'-(Chlorosulfonyl)acetanilide
• 4-(Acetylamino)Benzenesulfonyl Chloride
• 4-(Acetylamino)phenylsulfonyl chloride
• 4-Acetamidobenzene-1-sulfonyl chloride
• 4-Acetamidobenzenesulfonyl chloride
• 4-Acetamidophenylsulfonyl chloride
• 4-Chlorosulfonylacetanilide
• ASC
• Acetanilide-p-sulfonyl chloride
• Benzenesulfonyl chloride, 4-(acetylamino)-
• Chlorure de N-acetylsulfanilyle
• Dagenan chloride
• N-(4-Chlorosulfonylphenyl)acetamide
• N-Acetyl-p-aminobenzenesulfonyl chloride
• N-Acetylsulfanilylchlorid
• N-acetylsulphanilyl chloride
• N4-Acetylsulfanilyl chloride
• N⁴-Acetylsulfanilyl chloride
• Nsc 127860
• Sulfanilyl chloride, N-acetyl-
• cloruro de N-acetilsulfanililo
• p-(Acetylamino)benzenesulfonyl chloride
• p-(Chlorosulfonyl)acetanilide
• p-Acetamidobenzenesulfonyl chloride
• p-Acetamidophenylsulfonyl chloride
• p-Acetoaminobenzenesulfochloride

4-Acetamidobenzenesulfonyl Chloride

CAS: 121-60-8

Formula: C₈H₈ClNO₃S

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 233.67

Ref: 3B-A0074

4-Acetamidobenzene-1-sulfonyl chloride

CAS: 121-60-8

Formula: C₈H₈ClNO₃S

Purity: 98%

Color and Shape: Solid

Molecular weight: 233.6720

Ref: IN-DA003SPA

4-Acetamidobenzenesulphonyl chloride

CAS: 121-60-8

4-Acetamidobenzenesulphonyl chloride

Formula: C₈H₈ClNO₃S

Purity: tech

Color and Shape: off-white solid

Molecular weight: 233.67g/mol

Ref: 54-OR5468

4-Acetamidobenzenesulfonyl chloride

CAS: 121-60-8

Formula: C₈H₈ClNO₃S

Purity: 95%

Color and Shape: Solid, Powder or Crystalline Powder

Molecular weight: 233.67

Ref: 10-F046695

4-(Acetylamino)benzenesulfonyl Chloride

Controlled Product

CAS: 121-60-8

Applications A sulfanilamide derivative of Chitosan with antifungal properties.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Tashiro, T., et al.: Bioorg. Med. Chem., 16, 8896 (2008), Alcalde, E., et al.: J. Med. Chem., 52, 675 (2009),

Formula: C₈H₈ClNO₃S

Color and Shape: Beige

Molecular weight: 233.67

Ref: TR-A170950

4-(Acetylamino)benzenesulfonyl chloride

CAS: 121-60-8

4-(Acetylamino)benzenesulfonyl chloride is a sulfonamide drug that is used to treat urinary tract infections. It inhibits bacterial growth by binding to the enzyme dihydropteroate synthase, which is required for the synthesis of folate and purine nucleotides. 4-(Acetylamino)benzenesulfonyl chloride also has been shown to inhibit the activity of human immunodeficiency virus reverse transcriptase and protease, as well as other enzymes such as phosphodiesterase. This drug also has pharmacokinetic properties, including high water solubility and low protein binding. These properties are necessary for treating infections in the urinary tract, where urine contains high concentrations of electrolytes. 4-(Acetylamino)benzenesulfonyl chloride binds to a specific antibody that reacts with the active form of this molecule and not with its inactive form or other structurally related molecules. This property makes it possible to detect

Formula: C₈H₈ClNO₃S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 233.67 g/mol

Ref: 3D-FA17100