Description:3-Nitrobenzoyl chloride, with the CAS number 121-90-4, is an aromatic acyl chloride characterized by the presence of a nitro group (-NO2) positioned at the meta position relative to the acyl chloride functional group (-C(=O)Cl) on a benzene ring. This compound typically appears as a yellow to brownish liquid or solid, depending on its purity and temperature. It is known for its reactivity, particularly in acylation reactions, where it can introduce the 3-nitrobenzoyl group into various substrates. The presence of the electron-withdrawing nitro group enhances the electrophilicity of the carbonyl carbon, making it more susceptible to nucleophilic attack. 3-Nitrobenzoyl chloride is soluble in organic solvents such as dichloromethane and ether but is generally insoluble in water. It is important to handle this compound with care, as it can be corrosive and may cause irritation to the skin, eyes, and respiratory system. Proper safety precautions, including the use of personal protective equipment, are essential when working with this chemical.
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