CAS 1210-81-7

5-Chloro-N,N,2-trimethyl-1H-indole-3-ethanamine

Description:

5-Chloro-N,N,2-trimethyl-1H-indole-3-ethanamine, with the CAS number 1210-81-7, is a chemical compound that belongs to the indole class of compounds, which are characterized by a bicyclic structure containing a fused benzene and pyrrole ring. This particular compound features a chloro substituent at the 5-position of the indole ring and an ethylamine side chain at the 3-position, along with three methyl groups attached to the nitrogen atom. The presence of the chloro group can influence the compound's reactivity and biological activity. It is typically a solid at room temperature and may exhibit properties such as solubility in organic solvents. The compound may be of interest in various fields, including medicinal chemistry and pharmacology, due to its potential biological activities. However, specific details regarding its toxicity, stability, and applications would require further investigation and context within scientific literature.

Formula: C₁₃H₁₇ClN₂

InChI: InChI=1S/C13H17ClN2/c1-9-11(6-7-16(2)3)12-8-10(14)4-5-13(12)15-9/h4-5,8,15H,6-7H2,1-3H3

InChI key: InChIKey=KSYMELKKLOFABL-UHFFFAOYSA-N

SMILES: C(CN(C)C)C=1C=2C(NC1C)=CC=C(Cl)C2

Synonyms:

• N,N-Dimethyl-2-(5-chloro-2-methylindol-3-yl)ethylamine
• ST 1936
• 1H-Indole-3-ethanamine, 5-chloro-N,N,2-trimethyl-
• Indole, 5-chloro-3-[2-(dimethylamino)ethyl]-2-methyl-
• 5-Chloro-N,N,2-trimethyl-1H-indole-3-ethanamine
• 5-Chloro-3-[2-(dimethylamino)ethyl]-2-methylindole oxalate
• ST1936,ST-1936
• ST1936
• ST 1936 oxalate
• 2-(5-chloro-2-methyl-1H-indol-3-yl)-N,N-dimethylethanamine

ST 1936

Controlled Product

CAS: 1210-81-7

Applications Serotonin 5-HT(6) receptor agonists and antagonists have been proposed as possible useful compounds in the treatment of psychiatric disorders such as depression (1). ST 1936 Oxalate is a 5-HT(6) receptor agonist and may be a potential antidepressant/anti-anhedonic drug (1,2).
References (1) Scheggi, S., et al.: Behav Brain Res. 224, 35 (2011) (2) Valentini, V., et al.: Neuropharmacology 60, 602 (2011)

Formula: C₁₃H₁₇ClN₂

Color and Shape: Neat

Molecular weight: 236.74

Ref: TR-S687203

ST 1936 Oxalate

Controlled Product

CAS: 1210-81-7

ST 1936 Oxalate is an antidepressant drug that belongs to the class of 5-HT4 receptor agonists. It has been shown to inhibit locomotor activity in mice and rats, as well as increase serotonin levels in the brain. ST 1936 Oxalate inhibits the release of dopamine, which may be responsible for its antidepressant effect. This drug also has a specific agonist effect on the 5-ht7 receptor, which may contribute to its efficacy against human pathogens with similar receptors.

Formula: C₁₃H₁₇ClN₂

Purity: Min. 95%

Molecular weight: 236.74 g/mol

Ref: 3D-BAA21081

ST1936

CAS: 1210-81-7

ST1936 (ST 1936 oxalate) is a 5-HT6 receptor agonist that stimulates cAMP, Ca2+, ERK1/2, and Fyn kinases by fully activating cloned human 5-HT6 receptors.

Formula: C₁₃H₁₇ClN₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 236.74

Ref: TM-T23396