CAS 121055-53-6

N(2),3-ethenodeoxyguanosine

Description:

N(2),3-ethenodeoxyguanosine is a modified nucleoside that is derived from deoxyguanosine, featuring an etheno group at the N(2) position and a double bond at the 3-position of the sugar moiety. This compound is of particular interest in the field of molecular biology and genetics due to its role as a DNA adduct, which can result from exposure to certain environmental carcinogens. The presence of the etheno modification can lead to mispairing during DNA replication, potentially resulting in mutations. N(2),3-ethenodeoxyguanosine is often studied in the context of its effects on DNA stability and integrity, as well as its implications in cancer research. Its chemical structure includes a purine base linked to a deoxyribose sugar, and it is soluble in polar solvents. The compound is typically analyzed using techniques such as high-performance liquid chromatography (HPLC) and mass spectrometry to assess its formation and repair mechanisms in biological systems. Understanding its characteristics is crucial for elucidating the molecular mechanisms underlying DNA damage and repair.

Formula: C₁₂H₁₃N₅O₄

InChI: InChI=1/C12H13N5O4/c18-4-7-6(19)3-8(21-7)17-5-14-9-10(20)15-12-13-1-2-16(12)11(9)17/h1-2,5-8,18-19H,3-4H2,(H,13,15,20)/t6-,7+,8?/m0/s1

Synonyms:

• N(2),3-Edguo
• 4H-Imidazo(2,1-b)purin-4-one, 1-(2-deoxy-beta-D-erythro-pentofuranosyl)-1,5-dihydro-
• 1-(2-deoxy-D-erythro-pentofuranosyl)-1H-imidazo[2,1-b]purin-4(5H)-one
• N(2),3-Ethenodeoxyguanosine

N2,3-Etheno-2'-deoxy Guanosine

CAS: 121055-53-6

Formula: C₁₂H₁₃N₅O₄

Molecular weight: 291.27

Ref: 4Z-G-2430

N2,3-Etheno-2''-deoxy guanosine

CAS: 121055-53-6

Ref: 7W-GC1422

N2,3-Etheno-2'-Deoxy Guanosine-d3

CAS: 121055-53-6

Formula: C₁₂H₁₀D₃N₅O₄

Molecular weight: 294.29

Ref: 4Z-G-2431

2'-Deoxy-N2,3-ethenoguanosine

CAS: 121055-53-6

2'-Deoxy-N2,3-ethenoguanosine is a novel antiviral agent that is phosphorylated by the viral enzyme ribonucleotide reductase and then incorporated into viral DNA. This compound is an activator of deoxyribonucleoside monophosphate activity and inhibits the synthesis of DNA and RNA. 2'-Deoxy-N2,3-ethenoguanosine has been shown to inhibit the growth of cancer cells in culture and may be useful for treating cancer.

Formula: C₁₂H₁₃N₅O₄

Purity: Min. 95%

Molecular weight: 291.26 g/mol

Ref: 3D-ND16718

N2,3-Etheno-2'-deoxy Guanosine-d3

Controlled Product

CAS: 121055-53-6

Formula: C₁₂D₃H₁₀N₅O₄

Color and Shape: Neat

Molecular weight: 294.281

Ref: TR-E678002