CAS 121057-86-1
:Erythromycin, 2'-phthalate (6CI)
Description:
Erythromycin, 2'-phthalate (6CI) is a derivative of erythromycin, a macrolide antibiotic known for its effectiveness against a variety of bacterial infections. This compound is characterized by the presence of a phthalate moiety, which enhances its solubility and stability compared to the parent erythromycin. It typically appears as a white to off-white powder and is soluble in organic solvents while exhibiting limited solubility in water. The chemical structure includes a lactone ring and multiple hydroxyl groups, contributing to its antibacterial activity by inhibiting bacterial protein synthesis. Erythromycin, 2'-phthalate is often used in pharmaceutical formulations, particularly in enteric-coated tablets, to protect the active ingredient from degradation in the acidic environment of the stomach. Its pharmacokinetics may differ from that of erythromycin, with altered absorption and bioavailability profiles. As with other macrolides, it may exhibit side effects such as gastrointestinal disturbances and potential interactions with other medications due to its effects on liver enzymes. Overall, erythromycin, 2'-phthalate serves as a valuable compound in the treatment of infections, particularly in patients with penicillin allergies.
Formula:C45H71NO16
Synonyms:- Erythromycin Impurity 18
- Erythromycin, 2'-phthalate (6CI)
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