CAS 121058-82-0

5'-O-(4,4'-Dimethoxytrityl)-N4-acetyl-2'-deoxycytidine

Description:

5'-O-(4,4'-Dimethoxytrityl)-N4-acetyl-2'-deoxycytidine is a modified nucleoside that plays a significant role in the field of molecular biology and biochemistry, particularly in the synthesis of oligonucleotides. This compound features a deoxycytidine base, which is a building block of DNA, modified at the 5' position with a dimethoxytrityl (DMT) protecting group. The DMT group is commonly used to protect the hydroxyl group during the synthesis of nucleic acids, allowing for selective reactions at other sites. Additionally, the N4-acetyl modification enhances the stability and solubility of the nucleoside. The presence of these modifications contributes to its utility in various applications, including gene synthesis, PCR, and other nucleic acid-based technologies. The compound is typically characterized by its molecular weight, solubility in organic solvents, and stability under specific conditions, making it a valuable tool in synthetic biology and therapeutic development.

Formula: C₃₂H₃₃N₃O₇

Synonyms:

• N4-Acetyl-2'-deoxy-5'-O-DMT-D-cytidine
• N4-Acetyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine
• 5'-O-(4,4'-Dimethoxytrityl)-N4-acetyl-2'-deoxycytidine (synthetic)
• Dmt-Ac-dC
• 5'-DMTr-N4-acetyl-2'-deoxycytidine

Cytidine, n-acetyl-5'-o-[bis(4-methoxyphenyl)phenylmethyl]-

CAS: 121058-82-0

Formula: C₃₂H₃₃N₃O₈

Purity: 95%

Color and Shape: Solid

Molecular weight: 587.6197

Ref: IN-DA00749K

N4-Acetyl-5’-O-(4,4’-dimethoxytrityl)-2’-deoxycytidine

CAS: 121058-82-0

N4-Acetyl-5’-O-(4,4’-dimethoxytrityl)-2’-deoxycytidine

Purity: 95%

Ref: 54-OR1041998

N4-Acetyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine

CAS: 121058-82-0

Nucleoside Derivatives –Protectednucleosidesw/NH2/OH open

Formula: C₃₂H₃₃N₃O₈

Color and Shape: Solid

Molecular weight: 587.62

Ref: TM-TNU1464

N4-Acetyl-5'-O-DMT-cytidine

CAS: 121058-82-0

N4-Acetyl-5'-O-DMT-cytidine is an antiviral drug that inhibits the viral DNA polymerase. It is a modified nucleoside, which is activated by phosphorylation. N4-Acetyl-5'-O-DMT-cytidine is used in research for its anticancer properties and has shown to inhibit the growth of cancer cells in vitro. The compound was found to be more potent than cytidine and other modified nucleosides.

Formula: C₃₂H₃₃N₃O₈

Purity: Min. 98 Area-%

Color and Shape: White Powder

Molecular weight: 587.63 g/mol

Ref: 3D-NA11105