CAS 121058-85-3

2'-O-t-Butyldimethylsilyl-5'-O-(4,4'-dimethoxytrityl)-N4-acetyl cytidine

Description:

2'-O-t-Butyldimethylsilyl-5'-O-(4,4'-dimethoxytrityl)-N4-acetyl cytidine is a modified nucleoside, specifically a derivative of cytidine, which is a component of RNA. This compound features several protective groups that enhance its stability and facilitate its use in synthetic applications, particularly in oligonucleotide synthesis. The presence of the t-butyldimethylsilyl group at the 2' position provides protection against hydrolysis, while the 5'-O-(4,4'-dimethoxytrityl) group serves to protect the 5' hydroxyl during synthesis. The N4-acetyl modification adds steric bulk and can influence the nucleoside's reactivity and solubility. Overall, this compound is characterized by its increased stability, solubility in organic solvents, and utility in biochemical research and synthetic chemistry, particularly in the development of RNA-based therapeutics and diagnostics. Its structural modifications allow for selective reactions and improved handling in laboratory settings.

Formula: C₃₈H₄₇N₃O₈Si

Synonyms:

• 5'-Dmt-2'-Tbdms-Ac-Rc

2'-O-TBDMS-5'-O-DMT-N4-Ac cytidin

CAS: 121058-85-3

Formula: C₃₈H₄₇N₃O₈Si

Purity: 95%

Color and Shape: Solid

Molecular weight: 701.8806

Ref: IN-DA008YMI

N4-Acetyl-2''-O-tert-butyldimethylsilyl-5''-O-DMT-cytidine

CAS: 121058-85-3

Ref: 7W-GN3963

5'-O-DMT-2'-O-TBDMS-Ac-rC

CAS: 121058-85-3

5'-O-DMT-2'-O-TBDMS-Ac-rC

Purity: 98%

Molecular weight: 701.88g/mol

Ref: 54-OR1005528

5'-O-DMT-2'-O-TBDMS-Ac-rC

CAS: 121058-85-3

5’-O-DMT-2’-O-TBDMS-Ac-rC is a modified nucleoside and can be used to synthesize DNA or RNA.

Formula: C₃₈H₄₇N₃O₈Si

Color and Shape: Solid

Molecular weight: 701.892

Ref: TM-T37132

5′-O-DMT-2′-O-TBDMS-Ac-rC

CAS: 121058-85-3

Purity: 98%

Molecular weight: 701.892

Ref: 10-F987428

N4-Acetyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine

CAS: 121058-85-3

N4-Acetyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine is a novel modified nucleoside that is an activator of ribonucleosides. It has antiviral and anticancer activities, in addition to its potential as a DNA polymerase inhibitor. N4-Acetyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine is chemically synthesized with high purity and can be used for the synthesis of phosphoramidites for DNA synthesis. This compound also has the CAS number 12105885 3 and can be found in monophosphate form.

Formula: C₃₈H₄₇N₃O₈Si

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 701.88 g/mol

Ref: 3D-NA11979