CAS 121058-86-4

N-blocked-5'-O-DMT-2'-O-TBDMS CED adenosine phosphoramidit

Description:

N-blocked-5'-O-DMT-2'-O-TBDMS CED adenosine phosphoramidite, with the CAS number 121058-86-4, is a specialized chemical compound primarily used in the field of nucleic acid chemistry, particularly in the synthesis of oligonucleotides. This compound features several key functional groups that enhance its reactivity and stability during synthesis. The "N-blocked" designation indicates that the amine group is protected, preventing unwanted reactions during the synthesis process. The "5'-O-DMT" (dimethoxytrityl) group serves as a protective group for the 5' hydroxyl, allowing for selective coupling reactions. The "2'-O-TBDMS" (tert-butyldimethylsilyl) group protects the 2' hydroxyl, which is crucial for the stability of the ribose sugar during oligonucleotide synthesis. The "CED" (cyanoethyl diisopropylamino) moiety is involved in the phosphoramidite chemistry, facilitating the formation of phosphodiester bonds. Overall, this compound is essential for the efficient and controlled synthesis of RNA and DNA sequences in research and therapeutic applications.

Formula: C₅₄H₆₈N₇O₉PSi

Synonyms:

• 5'-Dimethoxytrityl-N-phenoxyacetyl-Adenosine, 2'-O-TBDMS-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
• N-blocked-5'-O-DMT-2'-O-TBDMS CED adenosine phosphoramidit

(2R,3R,4R,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-5-(6-(2-phenoxyacetamido)-9H-purin-9-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

CAS: 121058-86-4

(2R,3R,4R,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-5-(6-(2-phenoxyacetamido)-9H-purin-9-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

Purity: 95%

Molecular weight: 1018.24g/mol

Ref: 54-OR1046872