CAS 121062-08-6

melanotan

Description:

Melanotan, specifically referring to Melanotan II, is a synthetic peptide that is a derivative of the naturally occurring hormone alpha-melanocyte-stimulating hormone (α-MSH). It is primarily known for its ability to stimulate melanin production in the skin, leading to increased pigmentation. This characteristic has garnered interest for potential applications in tanning and photoprotection. Melanotan II is typically administered via subcutaneous injection and has been studied for its effects on appetite suppression and sexual function, although these uses are not officially approved. The compound is classified as a research chemical and is not approved for medical use by regulatory agencies. Its structure includes several amino acids, contributing to its biological activity. Users should be aware of potential side effects, which can include nausea, flushing, and increased libido, among others. Due to its unregulated status, the purity and safety of melanotan products can vary significantly, raising concerns about their use.

Formula: C₅₀H₆₉N₁₅O₉

InChI: InChI=1/C50H71N15O10/c1-3-4-16-36(59-29(2)66)44(70)65-41(25-42(67)68)49(75)64-40(24-32-27-55-28-58-32)48(74)62-38(22-30-13-6-5-7-14-30)46(72)61-37(19-12-21-56-50(53)54)45(71)63-39(23-31-26-57-34-17-9-8-15-33(31)34)47(73)60-35(43(52)69)18-10-11-20-51/h5-9,13-15,17,26-28,35-41,57H,3-4,10-12,16,18-25,51H2,1-2H3,(H2,52,69)(H,55,58)(H,59,66)(H,60,73)(H,61,72)(H,62,74)(H,63,71)(H,64,75)(H,65,70)(H,67,68)(H4,53,54,56)/t35-,36-,37-,38+,39-,40-,41-/m0/s1

Synonyms:

• Melanotan II
• N-Acetyl-L-norleucyl-L-alpha-aspartyl-L-histidyl-D-phenylalanyl-L-arginyl-L-tryptophyl-L-lysinamide (2->7)-lactam
• Ac-Nle-Asp-His-D-Phe-Arg-Trp-Lys-NH2
• Ac-[Nle4,Asp5,D-Phe7,Lys10]alpha-MSH-(4-10)-NH2
• MelanotanⅡ
• (3S,6S,9R,12S,15S,23S)-15-[(N-acetyl-L-norleucyl)amino]-9-benzyl-6-{3-[(diaminomethylidene)amino]propyl}-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexaazacyclotricosane-23-carboxamide
• N-acetyl-L-norleucyl-L-alpha-aspartyl-L-histidyl-D-phenylalanyl-N~5~-(diaminomethylidene)-L-ornithyl-L-tryptophyl-L-lysinamide
• Mt-Ii
• MTII, Melanotan II
• MelanotanⅡ Acetate
• MTII
• Ac-[Nle
• [ACETYL-NLE4, ASP5, D-PHE7, LYS10]-ALPHA-MELANOCYTE STIMULATING HORMONE (4-10) AMIDE
• AC-NLE-C[+ASP-HIS-DPHE-ARG-TRP-LYS]-NH2
• [ACETYL-NLE4, ASP5, D-PHE7, LYS10]-ALPHA-MSH (4-10) AMIDE
• AC-NLE-ASP-HIS-D-PHE-ARG-TRP-LYS-NH2, ASP5-LYS10, CYCLIC LACTAM
• AC-NLE4-C[ASP5, D-PHE7, LYS10]ALPHA-MSH (4-10)-NH2
• D-Phe
• AC-NLE-CYCLO(-BETA-ASP-HIS-D-PHE-ARG-TRP-EPSILON-LYS-NH2)
• 7
• MalanotanIi
• 10
• Mt-Ii(Melanotan)
• 4
• (AC-NLE4, ASP5, DPHE7, LYS10)-CYCLO-ALPHA-MSH (4-10) AMIDE
• Asp
• AC-NLE-CYCLO[(BETA-D)-HFRW-(EPSILON-K)]-NH2
• Lys
• 5
• [N-ACETYL-NLE4,ASP5,D-PHE7,LYS10]-ALPHA-MSH (4-10) AMIDE ASP5-LYS10, CYCLIC LACTAM
• 2
• AC-NLE-CYCLO(-ASP-HIS-D-PHE-ARG-TRP-LYS-NH2) ACETATE SALT
• Melanotan Ц
• ]α-MSH-(4-10)-NH
• Melanotan 2

Acetyl-(Nle⁴,Asp⁵,D-Phe⁷,Lys¹⁰)-cyclo-α-MSH (4-10) amide

CAS: 121062-08-6

Melanotan II, a cyclic MSH analog, is a potent full agonist of the melanocortin-3 and melanocortin-4 receptors (MC3-R and MC4-R). Intracerebroventricular administration of MTII inhibited feeding in four different mouse models of hyperphagia. MTII is a valuable tool for the study of the agouti obesity syndrome and of the role of melanocortinergic neurons in feeding.

Formula: C₅₀H₆₉N₁₅O₉

Purity: 98.6%

Color and Shape: White Powder

Molecular weight: 1024.19

Ref: 01-4039778

Melanotan II

CAS: 121062-08-6

Formula: C₅₀H₆₉N₁₅O₉

Purity: 95%

Color and Shape: Solid

Molecular weight: 1024.1780

Ref: IN-DA01DQ9V

Melanotan (MT)-II

CAS: 121062-08-6

Melanotan (MT)-II

Purity: ≥98%

Molecular weight: 1024.18g/mol

Ref: 54-BUP02167

Melanotan II acetate salt

CAS: 121062-08-6

Formula: C₅₀H₆₉N₁₅O₉

Purity: ≥ 95%

Color and Shape: White to off-white solid

Molecular weight: 1024.18

Ref: 7W-GK2597

MT-II

CAS: 121062-08-6

MT-II

Color and Shape: Solid

Molecular weight: 1,024.18g/mol

Ref: 54-BITH3035

Melanotan II

CAS: 121062-08-6

Formula: C₅₀H₆₉N₁₅O₉

Purity: 95%~99%

Color and Shape: White to Off-white Powder

Molecular weight: 1024.18

Ref: BP-BPPC017

Melanotan (MT)-II

CAS: 121062-08-6

Melanotan (MT)-II, a synthetic melanocortin receptor agonist, is a synthetic analogue of the peptide hormone α-melanocyte-stimulating hormone (α-MSH).

Formula: C₅₀H₆₉N₁₅O₉

Purity: >99.99%

Color and Shape: Solid

Molecular weight: 1024.18

Ref: TM-TP1324

Melanotan II Acetic Acid Salt

Controlled Product

CAS: 121062-08-6

Applications Melanotan II Acetic Acid Salt, is a lab-made chemical that is similar to a hormone found in people. Melanotan II has been shown to have melanogenesis (tanning) and aphrodisiac effects on humans.
References Hadley M.E., et al.: peptides, 26 (10), 1687 (2005); Dorr, R.T., et al.: Life, Sci, 58 (20), 1777 (1996); Wessells, H., et al.: Int. J. Impt Res., 12, 74 (2000);

Formula: C₅₀H₆₉N₁₅O₉·(xCH₃COOH)

Color and Shape: Neat

Molecular weight: 1024.186005

Ref: TR-M208750

Ac-Nle-Cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2

CAS: 121062-08-6

Ac-Nle-Cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2, also known as cycloastragenol, is a synthetic cyclic peptide that inhibits the activity of adipose β3 adrenergic receptors, leading to reduced fat accumulation. Cycloastragenol has been shown to inhibit the formation of atherosclerotic lesions in mice and may have antiatherogenic effects. It also has been shown to inhibit tumor growth in some skin cancer models and has immunosuppressive effects.

Formula: C₅₀H₆₉N₁₅O₉

Purity: Min. 95%

Molecular weight: 1,024.2 g/mol

Ref: 3D-PMC-3683-PI

Melanotan II

CAS: 121062-08-6

Melanocortin receptor agonist

Formula: C₅₀H₆₉N₁₅O₉

Purity: Min. 95%

Molecular weight: 1,024.18 g/mol

Ref: 3D-FA109114