CAS 121077-11-0

α,α-Difluoro-N-(2-hydroxyethyl)-2-nitro-1H-imidazole-1-propanamide

Description:

α,α-Difluoro-N-(2-hydroxyethyl)-2-nitro-1H-imidazole-1-propanamide, with CAS number 121077-11-0, is a chemical compound characterized by its unique structure that includes a nitro group, a difluoro substituent, and a hydroxyethyl side chain attached to an imidazole ring. This compound is typically classified as a pharmaceutical intermediate or a potential drug candidate due to its bioactive properties. The presence of the difluoro group enhances its lipophilicity and may influence its biological activity, while the hydroxyethyl group can contribute to solubility and interaction with biological targets. The imidazole ring is known for its role in various biological processes, including enzyme catalysis and as a building block in many pharmaceuticals. The compound's stability, reactivity, and potential applications in medicinal chemistry make it of interest for further research, particularly in the development of therapeutics targeting specific biological pathways. Safety and handling precautions should be observed, as with all chemical substances, due to potential toxicity or reactivity.

Formula: C₈H₁₀F₂N₄O₄

InChI: InChI=1S/C8H10F2N4O4/c9-8(10,6(16)11-2-4-15)5-13-3-1-12-7(13)14(17)18/h1,3,15H,2,4-5H2,(H,11,16)

InChI key: InChIKey=VOXUFOPZGRTSJY-UHFFFAOYSA-N

SMILES: N(=O)(=O)C=1N(CC(C(NCCO)=O)(F)F)C=CN1

Synonyms:

• KU 2285
• α,α-Difluoro-N-(2-hydroxyethyl)-2-nitro-1H-imidazole-1-propanamide
• NSC 635446
• 1H-Imidazole-1-propanamide, α,α-difluoro-N-(2-hydroxyethyl)-2-nitro-

KU-2285

CAS: 121077-11-0

KU-2285

Purity: ≥98%

Molecular weight: 264.19g/mol

Ref: 54-BUP01094

KU-2285

CAS: 121077-11-0

KU-2285: potent radiosensitizer, effective <100 mg/kg, outperforms MISO/SR-2508 in SCCVII tumors, clinical trials since late '90s.

Formula: C₈H₁₀F₂N₄O₄

Purity: 99% - 99.06%

Color and Shape: Solid

Molecular weight: 264.19

Ref: TM-T32427