The chemical substance known as 5-[2-[[4-[(4-Fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxy-7-quinolinyl]oxy]ethyl]-5-azaspiro[2.4]heptan-7-ol, with the CAS number 1210828-09-3, is characterized by its complex molecular structure, which includes multiple functional groups and a spirocyclic framework. This compound features an azaspiro structure, indicating the presence of a nitrogen atom within a spirocyclic arrangement, which contributes to its unique three-dimensional conformation. The presence of a fluoro group and methoxy group suggests potential for varied reactivity and biological activity, making it of interest in medicinal chemistry. Additionally, the indole and quinoline moieties may impart specific pharmacological properties, as these structures are often associated with diverse biological activities. The compound's solubility, stability, and reactivity would depend on its specific functional groups and overall molecular interactions. Overall, this substance represents a complex organic molecule with potential applications in drug development and research.

5-[2-[[4-[(4-Fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxy-7-quinolinyl]oxy]ethyl]-5-azaspiro[2.4]heptan-7-ol

1210828-09-3: The chemical substance known as 5-[2-[[4-[(4-Fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxy-7-quinolinyl]oxy]ethyl]-5-azaspiro[2.4]heptan-7-ol, with the CAS number 1210828-09-3, is characterized by its complex molecular structure, which includes multiple functional groups and a spirocyclic framework. This compound features an azaspiro structure, indicating the presence of a nitrogen atom within a spirocyclic arrangement, which contributes to its unique three-dimensional conformation. The presence of a fluoro group and methoxy group suggests potential for varied reactivity and biological activity, making it of interest in medicinal chemistry. Additionally, the indole and quinoline moieties may impart specific pharmacological properties, as these structures are often associated with diverse biological activities. The compound's solubility, stability, and reactivity would depend on its specific functional groups and overall molecular interactions. Overall, this substance represents a complex organic molecule with potential applications in drug development and research.

<p>Veonetinib (example 3) is an effective inhibitor of tyrosine kinase , exhibiting IC50 values of 0.1 μM and 0.4 μM in A549 cells and LOVO cells, respectively.</p>

CAS 1210828-09-3

5-[2-[[4-[(4-Fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxy-7-quinolinyl]oxy]ethyl]-5-azaspiro[2.4]heptan-7-ol

Veonetinib

Ref: TM-T200831