CAS 121104-96-9

Celgosivir

Description:

Celgosivir, with the CAS number 121104-96-9, is an antiviral compound primarily investigated for its potential in treating viral infections, particularly those caused by the hepatitis C virus (HCV). It functions as a glycosylation inhibitor, disrupting the glycosylation process of viral proteins, which is crucial for the virus's replication and infectivity. Celgosivir has been studied for its ability to enhance the immune response against viral infections. The compound is characterized by its specific molecular structure, which includes a unique sugar moiety that contributes to its mechanism of action. In terms of solubility, Celgosivir exhibits moderate solubility in various solvents, which is an important factor for its bioavailability and therapeutic efficacy. Its pharmacokinetic properties, including absorption, distribution, metabolism, and excretion, are essential for determining its potential as a therapeutic agent. Overall, Celgosivir represents a promising avenue in antiviral research, although further studies are necessary to fully understand its efficacy and safety profile in clinical settings.

Formula: C₁₂H₂₁NO₅

InChI: InChI=1S/C12H21NO5/c1-2-3-9(15)18-8-6-13-5-4-7(14)10(13)12(17)11(8)16/h7-8,10-12,14,16-17H,2-6H2,1H3/t7-,8-,10+,11+,12+/m0/s1

InChI key: InChIKey=HTJGLYIJVSDQAE-VWNXEWBOSA-N

SMILES: O[C@@H]1[C@@]2(N(C[C@H](OC(CCC)=O)[C@H]1O)CC[C@@H]2O)[H]

Synonyms:

• (1S,6S,7S,8R,8aR)-1,7,8-trihydroxyoctahydroindolizin-6-yl butanoate
• (1S,6S,7S,8R,8aR)-Octahydro-1,7,8-trihydroxy-6-indolizinyl butyrate
• 6-O-Butanoylcastanospermine
• 6-O-Butyrylcastanospermine
• BuCast
• Butanoic acid, (1S,6S,7S,8R,8aR)-octahydro-1,7,8-trihydroxy-6-indolizinyl ester
• Butanoic acid, octahydro-1,7,8-trihydroxy-6-indolizinyl ester, (1S-(1alpha,6beta,7alpha,8beta,8abeta))-
• Butanoic acid, octahydro-1,7,8-trihydroxy-6-indolizinyl ester, [1S-(1α,6β,7α,8β,8aβ)]-
• Celgosivir [INN]
• Mdl 28574
• Unii-895Vg117Hn

Celgosivir

CAS: 121104-96-9

Formula: C₁₂H₂₁NO₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 259.2988

Ref: IN-DA008TF0

Celgosivir

CAS: 121104-96-9

Celgosivir

Purity: ≥98%

Molecular weight: 259.3g/mol

Ref: 54-BUP02497

Celgosivir

CAS: 121104-96-9

Applications Celgosivir is an α-glucosidase I inhibitor.

Formula: C₁₂H₂₁NO₅

Color and Shape: Neat

Molecular weight: 259.3

Ref: TR-C256505

Celgosivir

CAS: 121104-96-9

Iminosugar; anti-viral; active against DENV infection

Formula: C₁₂H₂₁NO₅

Purity: Min. 95 Area-%

Color and Shape: White Powder

Molecular weight: 259.3 g/mol

Ref: 3D-FC45099

Celgosivir

CAS: 121104-96-9

Celgosivir (6 O-butanoyl castanospermine) is an inhibitor of α-glucosidase I. In vitro assay, it inhibits bovine viral diarrhoea virus (BVDV) ( IC50: 1.27 μM ).

Formula: C₁₂H₂₁NO₅

Purity: 98.03%

Color and Shape: Solid

Molecular weight: 259.3

Ref: TM-T10755L