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CAS 121148-00-3

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N-Boc-trans-4-amino-L-proline methyl ester

Description:
N-Boc-trans-4-amino-L-proline methyl ester is a chemical compound characterized by its structure, which includes a Boc (tert-butyloxycarbonyl) protecting group, a trans-4-amino configuration, and a methyl ester functional group. This compound is a derivative of proline, an amino acid that plays a crucial role in protein synthesis and is known for its unique cyclic structure. The Boc group serves as a protective moiety for the amino group, facilitating various synthetic applications by preventing unwanted reactions during chemical transformations. The trans configuration of the amino acid backbone contributes to its conformational stability, making it useful in peptide synthesis and drug development. N-Boc-trans-4-amino-L-proline methyl ester is often employed in the synthesis of more complex molecules, particularly in the field of medicinal chemistry, due to its ability to introduce proline-like features into peptides. Its solubility and reactivity can vary based on the solvent and conditions used, making it a versatile intermediate in organic synthesis.
Formula:C11H20N2O4
InChI:InChI=1/C11H20N2O4/c1-11(2,3)17-10(15)13-6-7(12)5-8(13)9(14)16-4/h7-8H,5-6,12H2,1-4H3/t7-,8+/m1/s1
Synonyms:
  • trans-4-Amino-1-Boc-2-pyrrolidinecarboxylic acid methyl ester
  • (2S,4R)-1-tert-butyl 2-methyl 4-aminopyrrolidine-1,2-dicarboxylate
  • 1-tert-butyl 2-methyl (2R,4S)-4-aminopyrrolidine-1,2-dicarboxylate
  • O1-tert-butyl O2-methyl (2S,4R)-4-aminopyrrolidine-1,2-dicarboxylate
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