CAS 12126-59-9

Estrogens, conjugated

Description:

Conjugated estrogens, identified by the CAS number 12126-59-9, are a mixture of estrogen hormones derived primarily from the urine of pregnant mares. These compounds are used therapeutically in hormone replacement therapy, particularly for alleviating menopausal symptoms and preventing osteoporosis in postmenopausal women. The primary characteristics of conjugated estrogens include their ability to bind to estrogen receptors, thereby exerting effects on various tissues, including the reproductive system, bones, and cardiovascular system. They are typically administered orally or via injection and can influence the menstrual cycle, promote the development of secondary sexual characteristics, and support overall reproductive health. Conjugated estrogens are known for their pharmacokinetic properties, including metabolism primarily in the liver and excretion through urine. While effective, their use is associated with potential side effects and risks, such as thromboembolic events and certain cancers, necessitating careful consideration and monitoring by healthcare providers. Overall, conjugated estrogens play a significant role in women's health, particularly in managing hormonal imbalances associated with menopause.

Formula: Unspecified

InChI: InChI=1/C18H22O5S.Na/c1-18-9-8-14-13-5-3-12(23-24(20,21)22)10-11(13)2-4-15(14)16(18)6-7-17(18)19;/h3,5,10,14-16H,2,4,6-9H2,1H3,(H,20,21,22);/q;+1/p-1/t14?,15?,16?,18-;/m0./s1

SMILES: CC12CCC3c4ccc(cc4CCC3C1CCC2=O)OS(=O)(=O)O.[Na]

Synonyms:

• Ayerogen
• Ayerogen Crema Vaginal
• Azumon
• C.E.S.
• Cenestin
• Climarest
• Conjugated Estrogens
• Conjugated equine estrogen
• Conjugates, estrogens
• Conjugen
• Dagynil
• Emopremarin
• Equin
• Estrogens, Conjugated
• Estrogens, Conjugated Synthetic A
• Estrogens, conjugates
• Femavit
• Hyphorin
• Mannest
• Menopak E
• Menpoz
• Neo-Menovar
• Oestro-Feminal
• Ovest
• Premaril
• Premarin
• Premarin Crema V
• Premarin Creme
• Premarin Vaginal Creme
• Premarina
• Premarose
• Presomen
• Prevagin-Premaril
• Romeda
• Sefac
• Sodium (8Ξ,9Ξ,14Ξ)-17-Oxoestra-1,3,5(10)-Trien-3-Yl Sulfate
• Sodium 17-Oxoestra-1,3,5(10),7-Tetraen-3-Yl Sulfate
• Srogen
• Sukingpo
• Transannon
• sodium (8ξ,9ξ,14ξ)-17-oxoestra-1,3,5(10)-trien-3-yl sulfate
• estropan
• CONJUGATED ESTROGEN
• cee
• conjes
• conjugatedequineestrogen
• estratab
• estrocon
• co-estro
• climestrone
• equigyne
• conestron
• conest
• estromed
• conjutabs
• estroate
• conjugatedestrogenichormones

Conjugated Estrogens

CAS: 12126-59-9

Ref: 3W-CS-BB-00008

Conjugated Estrogen sodium

CAS: 12126-59-9

Conjugated estrogens treat menopause symptoms, vaginal changes, and certain cancers.

Formula: C₁₈H₁₉NaO₅S

Purity: 98%

Color and Shape: White Needle Crystal

Molecular weight: 370.39

Ref: TM-T19988

Conjugated estrogens

CAS: 12126-59-9

Conjugated estrogens are a form of estrogen that is metabolized in the body. They are used for the treatment of postmenopausal symptoms, such as hot flashes and vaginal dryness, and also to prevent osteoporosis. Conjugated estrogens are given to women who have had their uterus surgically removed (hysterectomy) and to those who have had their ovaries removed (oophorectomy). Conjugated estrogens act by replacing the natural estrogen in the body, which is lost after menopause. The physiological effects of conjugated estrogens include increased energy metabolism and an increase in HDL cholesterol levels. These hormones can be detected in sewage effluent and wastewater treatment plants, which may lead to estrogenic effects on women who work there or use these water supplies.

Formula: C₁₈H₁₉NaO₅S

Purity: Min. 95%

Color and Shape: Solid

Molecular weight: 370.4 g/mol

Ref: 3D-FC39669