CAS 121264-05-9

pacidamycin 1

Description:

Pacidamycin 1, with the CAS number 121264-05-9, is a naturally occurring antibiotic that belongs to the class of compounds known as aminoglycosides. It is produced by certain strains of the bacterium Micromonospora. This compound exhibits a unique structure characterized by a complex bicyclic core, which is essential for its biological activity. Pacidamycin 1 is known for its ability to inhibit bacterial protein synthesis, making it effective against a range of Gram-positive and some Gram-negative bacteria. Its mechanism of action involves binding to the bacterial ribosome, disrupting the translation process. Additionally, pacidamycin 1 has shown potential in combating antibiotic-resistant strains, highlighting its significance in the field of medicinal chemistry. The compound's stability, solubility, and pharmacokinetic properties are crucial for its therapeutic applications, although further research is needed to fully understand its efficacy and safety profiles in clinical settings. Overall, pacidamycin 1 represents an important area of study in the development of new antimicrobial agents.

Formula: C₄₁H₅₀N₁₀O₁₂

InChI: InChI=1/C41H50N10O12/c1-20(42)31(53)17-30(49(3)36(57)28(46-35(56)21(2)43)14-22-7-6-8-24(52)13-22)34(44)37(58)51(19-25-16-32(54)38(63-25)50-12-11-33(55)48-41(50)62)40(61)47-29(39(59)60)15-23-18-45-27-10-5-4-9-26(23)27/h4-13,18-21,28-30,32,34,38,45,52,54H,14-17,42-44H2,1-3H3,(H,46,56)(H,47,61)(H,59,60)(H,48,55,62)/b25-19+/t20-,21-,28-,29?,30?,32?,34?,38?/m0/s1

Synonyms:

• L-alanyl-N-{(4S)-4-amino-1-[1-amino-2-({[1-carboxy-2-(1H-indol-3-yl)ethyl]carbamoyl}{(E)-[5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-hydroxydihydrofuran-2(3H)-ylidene]methyl}amino)-2-oxoethyl]-3-oxopentyl}-3-hydroxy-N-methyl-L-phenylalaninamide
• A 68567
• Pacidamycin 1
• Butanamide, N-(((1-carboxy-2-(1H-indol-3-yl)ethyl)amino)carbonyl)alanyl-N3-(N-alanyl-3-hydroxyphenylalanyl)-N-((5-(3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)dihydro-4-hydroxy-2(3H)-furanylidene)methyl)-N3-methyl-2,3-diamino-
• A-68567

Pacidamycin I

CAS: 121264-05-9

Pacidamycin I is an antimicrobial nucleoside antibiotics. Pacidamycin I inhibits translocase I, a key enzyme in peptidoglycan assembly.

Formula: C₄₁H₅₀N₁₀O₁₂

Color and Shape: Solid

Molecular weight: 874.909

Ref: TM-T28288