CAS 121343-82-6

Fmoc-Glu-OH

Description:

Fmoc-Glu-OH, or Fmoc-glutamic acid, is a derivative of the amino acid glutamic acid, commonly used in peptide synthesis and research. The "Fmoc" (9-fluorenylmethoxycarbonyl) group serves as a protective group for the amino functionality, allowing for selective reactions at the carboxyl group during peptide assembly. This compound is characterized by its ability to form stable peptide bonds, making it valuable in the synthesis of peptides and proteins. Fmoc-Glu-OH is typically a white to off-white solid, soluble in organic solvents like dimethylformamide (DMF) and dimethyl sulfoxide (DMSO), but less soluble in water. Its molecular structure includes a carboxylic acid group, an amino group, and the Fmoc protecting group, which contributes to its stability and reactivity. The compound is widely utilized in solid-phase peptide synthesis (SPPS) due to its ease of deprotection under mild conditions, allowing for the efficient assembly of complex peptides. Safety data should be consulted for handling, as with all chemical substances.

Formula: C₂₀H₁₉NO₆

InChI: InChI=1/C20H19NO6/c22-18(23)10-9-17(19(24)25)21-20(26)27-11-16-14-7-3-1-5-12(14)13-6-2-4-8-15(13)16/h1-8,16-17H,9-11H2,(H,21,26)(H,22,23)(H,24,25)/t17-/m0/s1

SMILES: c1ccc2c(c1)c1ccccc1C2COC(=N[C@@H](CCC(=O)O)C(=O)O)O

Synonyms:

• FMOC-L-Glu-OH
• N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-l-glutamic acid
• Fmoc-L-glutamic acid
• N-(9H-Fluorene-9-ylmethoxycarbonyl)-L-glutamic acid
• FMOC-GLUTAMIC ACID
• N-FMOC-L-GLUTAMIC ACID
• FMOC-GLU-OH
• N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-L-GLUTAMIC ACID
• N-[(9H-Fluorene-9-ylmethoxy)carbonyl]-L-glutamic acid
• FMOC-GLU-OH 98+%
• N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-L-GLUTAMIC-ACID

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-glutamic Acid

CAS: 121343-82-6

Formula: C₂₀H₁₉NO₆

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 369.37

Ref: 3B-F0453

Fmoc-Glu-OH

CAS: 121343-82-6

Simultaneous Nα/α-carboxyl protection can be readily achieved by oxazolidine formation with aldehydes. The product obtained from Fmoc-Glu-OH, paraformaldehyde and TosOH as catalyst has been converted into Dab derivatives, γ-diazomethyl ketones, Nγ-glycosylated Gln, and N’-glycosylated Dab Nγ-ureas.

Formula: C₂₀H₁₉NO₆

Purity: 99.71%

Color and Shape: White

Molecular weight: 369.37

Ref: 01-4025278

Fmoc-Glu-OH

CAS: 121343-82-6

Formula: C₂₀H₁₉NO₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 369.3680

Ref: IN-DA00819O

Fmoc-Glu-OH

CAS: 121343-82-6

Ref: 7W-GM1673

N-Fmoc-L-Glutamic Acid

CAS: 121343-82-6

N-Fmoc-L-Glutamic Acid

Purity: 98%

Molecular weight: 369.37g/mol

Ref: 54-OR1014372

Fmoc-Glu-OH

CAS: 121343-82-6

M03410 - Fmoc-Glu-OH

Formula: C₂₀H₁₉NO₆

Purity: 95%

Color and Shape: Solid, White powder

Molecular weight: 369.373

Ref: 10-M03410

FMOC-L-Glutamic Acid extrapure, 99%

CAS: 121343-82-6

Formula: C₂₀H₁₉NO₆

Purity: min. 99%

Color and Shape: White, Crystalline powder

Molecular weight: 369.37

Ref: SR-86254

Fmoc-Glu-OH

CAS: 121343-82-6

Fmoc-Glu-OH is a carboxylate that is used in the synthesis of acidic, disulfide bond containing, conjugates. It has been shown to be an effective anticancer agent against MDA-MB-231 cells and other cancer cells. Fmoc-Glu-OH is an antimicrobial agent that inhibits the growth of bacteria by targeting intracellular targets. This drug also binds to bacterial 16S ribosomal RNA and prevents protein synthesis, leading to cell death in the target organism.

Formula: C₂₀H₁₉NO₆

Purity: Min. 95%

Color and Shape: White To Off-White Solid

Molecular weight: 369.37 g/mol

Ref: 3D-FF33488

N-Fmoc-L-glutamic acid, 95%

CAS: 121343-82-6

N-Fmoc-L-glutamic acid nonessential amino acid that is important to the mammalian central nervous system. It is also a neurotransmitter for cone photoreceptors in the human brain and is used as a treatment for patients who have liver disease accompanied by encephalopathy (a condition termed ‘hepati

Formula: C₂₀H₁₉NO₆

Purity: 95%

Color and Shape: White, Powder

Molecular weight: 369.37

Ref: 02-H62936