CAS 121470-24-4

Azithromycin monohydrate

Description:

Azithromycin monohydrate is a macrolide antibiotic derived from erythromycin, primarily used to treat various bacterial infections. It is characterized by its broad-spectrum activity against both Gram-positive and Gram-negative bacteria, making it effective for respiratory tract infections, skin infections, and sexually transmitted diseases. The chemical structure of azithromycin features a large lactone ring, which is crucial for its mechanism of action, as it inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit. Azithromycin monohydrate is typically presented as a white to off-white crystalline powder, which is soluble in water, facilitating its formulation into oral and intravenous medications. Its pharmacokinetics are notable for a long half-life, allowing for once-daily dosing and shorter treatment courses compared to other antibiotics. Additionally, azithromycin has anti-inflammatory properties, which can be beneficial in treating certain conditions beyond infections. However, like all antibiotics, its use should be guided by susceptibility patterns to minimize the risk of resistance development.

Formula: C₃₈H₇₄N₂O₁₃

InChI: InChI=1S/C38H72N2O12.H2O/c1-15-27-38(10,46)31(42)24(6)40(13)19-20(2)17-36(8,45)33(52-35-29(41)26(39(11)12)16-21(3)48-35)22(4)30(23(5)34(44)50-27)51-28-18-37(9,47-14)32(43)25(7)49-28;/h20-33,35,41-43,45-46H,15-19H2,1-14H3;1H2/t20-,21-,22+,23-,24-,25+,26+,27-,28+,29-,30+,31-,32+,33-,35+,36-,37-,38-;/m1./s1

Synonyms:

• Unii-jte4mnn1md
• Azithromycin monohydrate Q: What are the applications of
• 11-((4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2-ethyl-3,4,10-trihydroxy-13-((5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-3,5,6,8,10,12,14-heptamethyl-1-oxa-6-azacyclopentadecan-15-one hydrate
• 1-Oxa-6-azacyclopentadecan-15-one, 13-((2,6-dideoxy-3-C-methyl-3-o-methyl-alpha-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3- (dimethylamino)-beta-D-xylo-hexopyranosyl)oxy)-, monohydrate, (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-
• Azithromycin monohydrate
• Azithromycin Monohydrate
• Azithromycin monohydrate Q: What is the storage condition of
• Azithromycin monohydrate Q: What is the CAS Number of
• Azithromycin monohydrateQ: What is