CAS 121524-08-1

Amibegron

Description:

Amibegron, with the CAS number 121524-08-1, is a chemical compound that belongs to the class of beta-adrenergic agonists. It is primarily recognized for its potential therapeutic applications in the treatment of respiratory conditions, such as asthma and chronic obstructive pulmonary disease (COPD), by promoting bronchodilation. The compound functions by selectively stimulating beta-2 adrenergic receptors, leading to relaxation of bronchial smooth muscle. Amibegron is characterized by its ability to enhance airflow and alleviate symptoms associated with airway obstruction. Additionally, it may exhibit a favorable pharmacokinetic profile, including a reasonable duration of action and minimal side effects compared to other beta-agonists. Its chemical structure features specific functional groups that contribute to its biological activity and receptor selectivity. As with many pharmacological agents, the safety and efficacy of Amibegron are evaluated through clinical trials, and its use is subject to regulatory approval in various jurisdictions.

Formula: C₂₂H₂₆ClNO₄

InChI: InChI=1S/C22H26ClNO4/c1-2-27-22(26)14-28-20-9-7-15-6-8-19(11-17(15)12-20)24-13-21(25)16-4-3-5-18(23)10-16/h3-5,7,9-10,12,19,21,24-25H,2,6,8,11,13-14H2,1H3/t19-,21-/m0/s1

InChI key: InChIKey=RDJQCOBTKKAQAH-FPOVZHCZSA-N

SMILES: N(C[C@H](O)C1=CC(Cl)=CC=C1)[C@@H]2CC=3C(=CC=C(OCC(OCC)=O)C3)CC2

Synonyms:

• Acetic acid, [[(7S)-7-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]-5,6,7,8-tetrahydro-2-naphthalenyl]oxy]-, ethyl ester
• Acetic acid, [[7-[[2-(3-chlorophenyl)-2-hydroxyethyl]amino]-5,6,7,8-tetrahydro-2-naphthalenyl]oxy]-, ethyl ester, [R-(R*,S*)]-
• Amibegron
• SR 58611

Amibegron

CAS: 121524-08-1

Amibegron: oral β3 adrenergic agonist, CNS-penetrating, with antidepressant and anxiolytic properties.

Formula: C₂₂H₂₆ClNO₄

Color and Shape: Solid

Molecular weight: 403.9

Ref: TM-T71216