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CAS 121548-04-7

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gelucire 44-14

Description:
Gelucire 44/14 is a non-ionic surfactant and excipient commonly used in pharmaceutical formulations, particularly for drug delivery systems. It is a glyceride derived from the combination of glycerol and fatty acids, specifically designed to enhance the solubility and bioavailability of poorly soluble drugs. Gelucire 44/14 exhibits characteristics such as a melting point that allows it to function effectively as a solid lipid excipient, providing a matrix for sustained release formulations. Its surfactant properties facilitate the emulsification of active pharmaceutical ingredients, improving their dispersion in aqueous environments. Additionally, Gelucire 44/14 is known for its compatibility with various other excipients and active ingredients, making it a versatile choice in formulation development. It is generally regarded as safe for use in pharmaceutical applications, with a favorable profile for oral and parenteral routes of administration. Overall, Gelucire 44/14 plays a crucial role in enhancing the performance of drug formulations, particularly in improving the delivery and absorption of therapeutic agents.
Synonyms:
  • Peg-32 glyceryl laurate
  • Gelucire 44-14
  • Gelucire 44/14
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Found 3 products.
  • CymitQuimica logo
    USP
    + Info

    Lauroyl Polyoxylglycerides 1500

    CAS:
    Fatty substances of animal or vegetable orgin and mixtures thereof not elsewhere specified or included
    Color and Shape:White Waxy Solid

    Ref: 45-1356950

  • Gelucire 44/14
    Targetmol
    + Info

    Gelucire 44/14

    CAS:
    <p>Gelucire 44/14 (Gelucire 14/44) acts as a nonionic surface-active excipient and improves fat absorption in rats with impaired lipolysis.</p>
    Purity:96.00%
    Color and Shape:Solid

    Ref: TM-T19338

  • Gelucire 44/14
    Biosynth
    + Info

    Gelucire 44/14

    CAS:
    <p>Gelucire 44/14 is a pluronic block copolymer composed of a polyoxyethylene-polyoxypropylene glycol with an acyl chain. It is used as an absorption enhancer and excipient in pharmaceuticals, especially for small-molecule drugs that are not water-soluble. The drug is dispersed as particles and mixed with crystalline cellulose (CC) to produce a uniform mixture that is then compressed into tablets or capsules. CC acts as an antiadherent, preventing the adhesion of the drug particles to each other during compression. Gelucire 44/14 also has the ability to inhibit enzymes that are involved in lipid metabolism and prostaglandin synthesis.</p>
    Purity:Min. 90%
    Color and Shape:Clear Liquid

    Ref: 3D-FG178150

    100g
    863.00€