CAS 121569-61-7: (3S,9S,10R,11R,13R)-2,3,10,11,12,13-Hexahydro-3-hydroxy-10-methoxy-9-methyl-11-(methylamino)-9,13-epoxy-1H,9H-diindolo[1,2,3-gh:3′,2′,1′-lm]pyrrolo[3,4-j][1,7]benzodiazonin-1-one

Description: The chemical substance with the name "(3S,9S,10R,11R,13R)-2,3,10,11,12,13-Hexahydro-3-hydroxy-10-methoxy-9-methyl-11-(methylamino)-9,13-epoxy-1H,9H-diindolo[1,2,3-gh:3′,2′,1′-lm]pyrrolo[3,4-j][1,7]benzodiazonin-1-one" and CAS number "121569-61-7" is a complex organic compound characterized by its intricate polycyclic structure, which includes multiple fused indole and pyrrole rings. This compound features several functional groups, including hydroxyl, methoxy, and methylamino groups, contributing to its potential biological activity. The stereochemistry indicated by the specific configuration at various chiral centers suggests that the compound may exhibit unique interactions with biological targets, possibly influencing its pharmacological properties. Its epoxy group may also play a role in reactivity and stability. Due to its structural complexity, this substance may be of interest in medicinal chemistry and pharmacology, particularly in the development of novel therapeutic agents. However, detailed studies would be necessary to fully understand its properties, mechanisms of action, and potential applications.

Formula: C₂₈H₂₆N₄O₄

InChI: InChI=1S/C28H26N4O4/c1-28-25(35-3)15(29-2)12-18(36-28)31-16-10-6-4-8-13(16)19-21-22(27(34)30-26(21)33)20-14-9-5-7-11-17(14)32(28)24(20)23(19)31/h4-11,15,18,25,27,29,34H,12H2,1-3H3,(H,30,33)/t15-,18-,25-,27+,28+/m1/s1

InChI key: InChIKey=PBCZSGKMGDDXIJ-KRUBCLEUSA-N

SMILES: O=C1NC(O)C=2C1=C3C4=CC=CC=C4N5C3=C6C2C=7C=CC=CC7N6C8(OC5CC(NC)C8OC)C

Synonyms:

• 7-epi-Hydroxystaurosporine
• (3S,9S,10R,11R,13R)-2,3,10,11,12,13-Hexahydro-3-hydroxy-10-methoxy-9-methyl-11-(methylamino)-9,13-epoxy-1H,9H-diindolo[1,2,3-gh:3′,2′,1′-lm]pyrrolo[3,4-j][1,7]benzodiazonin-1-one
• 9,13-Epoxy-1H,9H-diindolo[1,2,3-gh:3′,2′,1′-lm]pyrrolo[3,4-j][1,7]benzodiazonin-1-one, 2,3,10,11,12,13-hexahydro-3-hydroxy-10-methoxy-9-methyl-11-(methylamino)-, (3S,9S,10R,11R,13R)-
• UCN 02
• 9,13-Epoxy-1H,9H-diindolo[1,2,3-gh:3′,2′,1′-lm]pyrrolo[3,4-j][1,7]benzodiazonin-1-one, 2,3,10,11,12,13-hexahydro-3-hydroxy-10-methoxy-9-methyl-11-(methylamino)-, [3S-(3α,9α,10β,11β,13α)]-

9,13-Epoxy-1H,9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-1-one, 2,3,10,11,12,13-hexahydro-3-hydroxy-10-methoxy-9-methyl-11-(methylamino)-, (3S,9S,10R,11R,13R)-

CAS: 121569-61-7

• Formula: C₂₈H₂₆N₄O₄
• Color and Shape: Liquid
• Molecular weight: 482.5304

7-β-Hydroxystaurosporine (UCN-02)

CAS: 121569-61-7

• Formula: C₂₈H₂₆N₄O₄
• Color and Shape: Pale Yellow Solid
• Molecular weight: 482.54

UCN-02

CAS: 121569-61-7

• Formula: C₂₈H₂₆N₄O₄
• Color and Shape: Neat
• Molecular weight: 482.53

UCN-02

CAS: 121569-61-7

UCN-02 (7-epi-Hydroxystaurosporine) is a PKC inhibitor produced by Streptomyces N-126 strain, which inhibits PKA.

• Formula: C₂₈H₂₆N₄O₄
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 482.53