Boc-Ala-Ala-Pro-Ala-pNA, with the CAS number 121570-42-1, is a synthetic peptide compound that features a sequence of amino acids, specifically two alanines (Ala), one proline (Pro), and a para-nitroanilide (pNA) moiety. The "Boc" (tert-butyloxycarbonyl) group serves as a protective group for the amino terminus, facilitating peptide synthesis by preventing unwanted reactions. This compound is often utilized in biochemical research, particularly in studies involving proteolytic enzymes, as the pNA group can be cleaved to release a chromogenic product, allowing for the quantification of enzymatic activity. The presence of the proline residue introduces a unique conformational characteristic, influencing the peptide's secondary structure and stability. Additionally, Boc-Ala-Ala-Pro-Ala-pNA is typically soluble in organic solvents and may exhibit specific interactions with biological targets, making it valuable in drug design and development. Its properties, such as molecular weight and solubility, can vary based on the specific conditions of use, including pH and solvent composition.

Boc-Ala-Ala-Pro-Ala-pNA

121570-42-1: Boc-Ala-Ala-Pro-Ala-pNA, with the CAS number 121570-42-1, is a synthetic peptide compound that features a sequence of amino acids, specifically two alanines (Ala), one proline (Pro), and a para-nitroanilide (pNA) moiety. The "Boc" (tert-butyloxycarbonyl) group serves as a protective group for the amino terminus, facilitating peptide synthesis by preventing unwanted reactions. This compound is often utilized in biochemical research, particularly in studies involving proteolytic enzymes, as the pNA group can be cleaved to release a chromogenic product, allowing for the quantification of enzymatic activity. The presence of the proline residue introduces a unique conformational characteristic, influencing the peptide's secondary structure and stability. Additionally, Boc-Ala-Ala-Pro-Ala-pNA is typically soluble in organic solvents and may exhibit specific interactions with biological targets, making it valuable in drug design and development. Its properties, such as molecular weight and solubility, can vary based on the specific conditions of use, including pH and solvent composition.

L-Alaninamide, N-[(1,1-dimethylethoxy)carbonyl]-L-alanyl-L-alanyl-L-prolyl-N-(4-nitrophenyl)- (9CI)

<p>Boc-Ala-Ala-Pro-Ala-pNA is a synthetic peptide analog of the amino acid sequence Pro-Gly-Arg. It has been shown to inhibit the proliferation of prostate cancer cells, as well as to inhibit tumor growth in animals. This peptide also inhibits protease activity in subtilisin and has been used to study the inhibition of angiogenesis by endothelial cell proliferation. The peptide is an inhibitor of ion exchange and has been used to study the effects of fatty acids on carcinoma cell lines. Boc-Ala-Ala-Pro-Ala-pNA has also been shown to be active against other animal cells and could be used for research purposes.</p>

CAS 121570-42-1

Boc-Ala-Ala-Pro-Ala-pNA

L-Alaninamide, N-[(1,1-dimethylethoxy)carbonyl]-L-alanyl-L-alanyl-L-prolyl-N-(4-nitrophenyl)- (9CI)

Ref: IN-DA0015B5

Boc-Ala-Ala-Pro-Ala-pNA

Ref: 3D-FB110712