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CAS 121573-36-2

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10,10-difluorothromboxane A2

Description:
10,10-Difluorothromboxane A2 is a synthetic analog of thromboxane A2, a potent lipid mediator involved in various physiological processes, particularly in platelet aggregation and vasoconstriction. This compound features two fluorine atoms substituted at the 10-position of the thromboxane structure, which can significantly influence its biological activity and stability. The presence of fluorine atoms often enhances the lipophilicity and metabolic stability of the molecule, potentially affecting its interaction with thromboxane receptors. As a thromboxane analog, 10,10-difluorothromboxane A2 may exhibit similar pharmacological effects, including promoting platelet aggregation and influencing vascular tone. However, the specific characteristics, such as its potency, selectivity, and pharmacokinetics, would depend on detailed experimental studies. Its CAS number, 121573-36-2, allows for precise identification in chemical databases and literature. Overall, this compound serves as a valuable tool in research related to thromboxane biology and its implications in cardiovascular health.
Formula:C20H30F2O5
InChI:InChI=1/C20H30F2O5/c1-2-3-6-9-14(23)12-13-16-15(10-7-4-5-8-11-17(24)25)18-20(21,22)19(26-16)27-18/h4,7,12-16,18-19,23H,2-3,5-6,8-11H2,1H3,(H,24,25)/b7-4-,13-12+/t14-,15+,16+,18-,19-/m0/s1
Synonyms:
  • 10,10-Difluoro-txa2
  • (5Z)-7-{(1S,3R,4R,5S)-7,7-difluoro-3-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-2,6-dioxabicyclo[3.1.1]hept-4-yl}hept-5-enoic acid (non-preferred name)
  • 10,10-Difluorothromboxane A2
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