CAS 1215821-44-5

Fexofenadine-d10 Hydrochloride

Description:

Fexofenadine-d10 Hydrochloride is a deuterated form of fexofenadine, an antihistamine commonly used to alleviate allergy symptoms such as hay fever and hives. The "d10" designation indicates that this compound contains ten deuterium atoms, which are isotopes of hydrogen, replacing regular hydrogen atoms in the molecular structure. This modification can be useful in pharmacokinetic studies and metabolic research, as it allows for the tracking of the compound in biological systems. Fexofenadine itself is a selective antagonist of peripheral H1 receptors, which helps reduce allergic responses without causing significant sedation, a common side effect of many first-generation antihistamines. The hydrochloride salt form enhances the solubility and stability of the compound. In terms of physical properties, fexofenadine-d10 Hydrochloride is typically a white to off-white crystalline powder, and it is soluble in water and various organic solvents. Its use in research and clinical settings is primarily focused on understanding the pharmacodynamics and pharmacokinetics of antihistamines.

Formula: C₃₂H₂₉D₁₀NO₄·ClH

Synonyms:

• [2H10]-Fexofenadine hydrochloride
• Fexofenadine-d10 Hydrochloride
• RRJFVPUCXDGFJB-MQHVTZQPSA-N

Fexofenadine-d10 HCl

CAS: 1215821-44-5

Formula: C₃₂H₂₉D₁₀NO₄·HCl

Color and Shape: White To Off-White Solid

Molecular weight: 511.73 36.46

Ref: 4Z-F-042

Fexofenadine Impurity 16

CAS: 1215821-44-5

Formula: C₃₈H₅₁NO₇

Color and Shape: White To Off-White Solid

Molecular weight: 633.83

Ref: 4Z-F-0428

Fexofenadine-d10 Hydrochloride

Controlled Product

CAS: 1215821-44-5

Applications Fexofenadine-d10 Hydrochloride is the labeled analogue of Fexofenadine Hydrochloride (F322490), the active metabolite of Terfenadine (T114500), a H1-histamine receptor antagonist.
References Pratt, E., et al.: Diabet Med., 18, 515 (2001); Mizutani, N., et al.: J. Pharmacol. Sci., 93, 437 (2003); Scadding, G., et al.: Clin. Drug Invest., 25, 153 (2005); Asai, M., et al.: N. Engl. J. Med., 354, 307 (2006)

Formula: C₃₂₂H₁₀H₂₉NO₄·ClH

Color and Shape: Neat

Molecular weight: 548.18

Ref: TR-F322492