6'-Exomethylene Simvastatin, identified by its CAS number 121624-18-8, is a derivative of simvastatin, which is a well-known statin used primarily for lowering cholesterol levels in the blood. This compound features a unique exomethylene group that enhances its pharmacological properties. Structurally, it contains a lactone ring, characteristic of statins, which is crucial for its mechanism of action as it inhibits HMG-CoA reductase, an enzyme involved in cholesterol biosynthesis. The presence of the exomethylene group may influence its solubility, stability, and bioavailability compared to its parent compound. In terms of physical properties, like many statins, it is expected to be a solid at room temperature, with potential for moderate lipophilicity, which aids in its absorption in biological systems. The compound's efficacy and safety profile would be evaluated through pharmacological studies, and it may exhibit similar side effects to other statins, such as muscle pain or liver enzyme alterations. Overall, 6'-Exomethylene Simvastatin represents a modification aimed at improving the therapeutic potential of simvastatin.

6'-EXOMETHYLENE SIMVASTATIN

121624-18-8: 6'-Exomethylene Simvastatin, identified by its CAS number 121624-18-8, is a derivative of simvastatin, which is a well-known statin used primarily for lowering cholesterol levels in the blood. This compound features a unique exomethylene group that enhances its pharmacological properties. Structurally, it contains a lactone ring, characteristic of statins, which is crucial for its mechanism of action as it inhibits HMG-CoA reductase, an enzyme involved in cholesterol biosynthesis. The presence of the exomethylene group may influence its solubility, stability, and bioavailability compared to its parent compound. In terms of physical properties, like many statins, it is expected to be a solid at room temperature, with potential for moderate lipophilicity, which aids in its absorption in biological systems. The compound's efficacy and safety profile would be evaluated through pharmacological studies, and it may exhibit similar side effects to other statins, such as muscle pain or liver enzyme alterations. Overall, 6'-Exomethylene Simvastatin represents a modification aimed at improving the therapeutic potential of simvastatin.

CAS 121624-18-8

6'-EXOMETHYLENE SIMVASTATIN

Simvastatin Impurity 11

Ref: 4Z-S-1214

6’-Exomethylene Simvastatin

Ref: TR-E959100