CAS 1216599-78-8
:N4-Hydroxymethyl Hydrochlorothiazide
Description:
N4-Hydroxymethyl Hydrochlorothiazide is a chemical compound that belongs to the thiazide class of diuretics, which are commonly used in the treatment of hypertension and edema. This substance is characterized by its thiazide structure, which includes a benzothiadiazine ring, and a hydroxymethyl group that enhances its pharmacological properties. The presence of the hydrochloride salt form indicates that it is a hydrochloride, which typically improves solubility and stability in aqueous solutions. N4-Hydroxymethyl Hydrochlorothiazide functions by inhibiting sodium reabsorption in the distal convoluted tubules of the kidneys, leading to increased excretion of sodium and water, thereby reducing blood volume and blood pressure. Its efficacy and safety profile make it a valuable agent in managing cardiovascular conditions. Additionally, the compound may exhibit various side effects, which are common to thiazide diuretics, including electrolyte imbalances and potential impacts on renal function. As with any medication, it is essential to use it under medical supervision to monitor for adverse effects and interactions with other drugs.
Formula:C8H10ClN3O5S2
Synonyms:- 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3,4-dihydro-4-(hydroxymethyl)-, 1,1-dioxide
- N4-Hydroxymethyl Hydrochlorothiazide
- 6-chloro-4-(hydroxymethyl)-1,1-dioxo-2,3-dihydro-1$l^{6},2,4-benzothiadiazine-7-sulfonamide
- 6-chloro-4-(hydroxymethyl)-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonamide 1,1-dioxide
- Hydrochlorothiazide N4-Hydroxymethyl
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