CAS 1216671-11-2

5-[2-ethoxy-5-[4-(trideuteriomethyl)piperazin-1-yl]sulfonylphenyl]-1-methyl-3-propyl-4H-pyrazolo[4,3-d]pyrimidine-7-thione

Description:

The chemical substance known as 5-[2-ethoxy-5-[4-(trideuteriomethyl)piperazin-1-yl]sulfonylphenyl]-1-methyl-3-propyl-4H-pyrazolo[4,3-d]pyrimidine-7-thione, with the CAS number 1216671-11-2, is a complex organic compound characterized by its multi-functional structure. It features a pyrazolo[4,3-d]pyrimidine core, which is a bicyclic compound known for its biological activity, particularly in medicinal chemistry. The presence of a sulfonyl group and an ethoxy substituent suggests potential solubility and reactivity enhancements, while the piperazine moiety may contribute to its pharmacological properties, often associated with central nervous system activity. The incorporation of trideuteriomethyl groups indicates isotopic labeling, which can be useful in studies involving metabolic pathways or pharmacokinetics. Overall, this compound's intricate structure suggests it may have applications in drug development, particularly in targeting specific biological pathways or receptors. Its unique characteristics warrant further investigation to elucidate its potential therapeutic effects and mechanisms of action.

Formula: C₂₂H₂₇D₃N₆O₃S₂

Synonyms:

• 5-[2-ethoxy-5-[4-(trideuteriomethyl)piperazin-1-yl]sulfonylphenyl]-1-methyl-3-propyl-4H-pyrazolo[4,3-d]pyrimidine-7-thione
• [2H3]-Thiosildenafil

Thiosildenafil-d3

Controlled Product

CAS: 1216671-11-2

Applications An analog of labelled Sildenafil; a novel pyrazolopyrimidinethiones as PDE5 inhibitor.
References DeBono, R., et al.: Pharm. Technol., 26, 72 (2002), Blok-Tip, L., et al.: Food Addit. Contam., 21, 737 (2004), Liang, Q., et al.: J. Pharm. Biomed. Anal., 40, 305 (2006),

Formula: C₂₂H₂₇D₃N₆O₃S₂

Color and Shape: Off White Solid

Molecular weight: 493.66

Ref: TR-T371502