CAS 1216920-18-1

Bibx 1382 dihydrochloride

CAS: 1216920-18-1

Bibx 1382 dihydrochloride is a liposome-encapsulated drug that binds to the extracellular domain of ICAM-1, which is a protein found on the surface of cancer cells. Bibx 1382 dihydrochloride slows the growth of cancer cells by binding to calmodulin, an intracellular protein, and inhibiting it from activating phosphatase 2A. This inhibition leads to reduced activation of protein kinase C and decreased production of cyclic AMP. Bibx 1382 dihydrochloride also inhibits the activity of tumor necrosis factor alpha (TNF-α), which is an inflammatory cytokine that causes inflammation and cell death in cancer cells. Bibx 1382 dihydrochloride has been shown to be effective against cancer cell lines in vitro and in vivo with a microfluidic device that encapsulates the drug.

Formula: C₁₈H₂₁Cl₃FN₇

Purity: Min. 95%

Molecular weight: 460.8 g/mol

Ref: 3D-RYB92018

BIBX 1382 Dihydrochloride

CAS: 1216920-18-1

BIBX 1382 Dihydrochloride blocks Lassa/Ebola entry, aids in studying virus-host interactions, and hints at kinase targets for therapy.

Formula: C₁₈H₂₁Cl₃FN₇

Color and Shape: Solid

Molecular weight: 460.76

Ref: TM-T30443