CAS 1217-67-0

2-[2,3-Dichloro-4-(1-oxobutyl)phenoxy]acetic acid

Description:

2-[2,3-Dichloro-4-(1-oxobutyl)phenoxy]acetic acid, with the CAS number 1217-67-0, is a synthetic organic compound primarily recognized for its application as a herbicide. This substance features a phenoxyacetic acid structure, which is characterized by the presence of a phenoxy group attached to an acetic acid moiety. The compound contains two chlorine atoms at the 2 and 3 positions of the aromatic ring, contributing to its biological activity and stability. The presence of a butyric acid derivative enhances its herbicidal properties, making it effective against a variety of broadleaf weeds. In terms of physical properties, it is typically a solid at room temperature and may exhibit moderate solubility in organic solvents while being less soluble in water. Its mode of action involves disrupting plant growth processes, specifically targeting the auxin hormone pathways. As with many herbicides, safety and environmental impact assessments are crucial for its use, necessitating adherence to regulatory guidelines to mitigate potential risks to non-target organisms and ecosystems.

Formula: C₁₂H₁₂Cl₂O₄

InChI: InChI=1/C12H12Cl2O4/c1-2-3-8(15)7-4-5-9(12(14)11(7)13)18-6-10(16)17/h4-5H,2-3,6H2,1H3,(H,16,17)

InChI key: InChIKey=FQAYODYTZPXLRH-UHFFFAOYSA-N

SMILES: C(CCC)(=O)C1=C(Cl)C(Cl)=C(OCC(O)=O)C=C1

Synonyms:

• (2,3-Dichloro-4-(1-oxobutyl)phenoxy)acetic acid
• (2,3-Dichloro-4-butyrylphenoxy)acetic acid
• (4-Butanoyl-2,3-Dichlorophenoxy)Acetic Acid
• 2-(4-Butanoyl-2,3-dichlorophenoxy)acetic acid
• 2-[2,3-Dichloro-4-(1-oxobutyl)phenoxy]acetic acid
• Acetic acid, (2,3-dichloro-4-(1-oxobutyl)phenoxy)-
• Acetic acid, (4-butyryl-2,3-dichlorophenoxy)-
• Acetic acid, 2-[2,3-dichloro-4-(1-oxobutyl)phenoxy]-
• Brn 1914291
• 4-Butyryl-2,3-dichlorophenoxyacetic acid
• USP related Substance A
• Etacrynic Acid Impurity 1 (Etacrynic Acid EP Impurity A)
• 4-Butanoyl-2, 3-dichlorophenoxy acetic acid
• Ethacrynic Acid impurity A
• 2-(4-Butyryl-2,3-dichlorophenoxy)acetic acid
• <2,3-dichloro-4-(1-oxobutyl)phenyloxy>acetic acid
• Etacrynic Acid EP Impurity A

Ethacrynic Acid Related Compound A ((4-Butyryl-2,3-dichlorophenoxy)acetic acid)

CAS: 1217-67-0

Carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides etc not elsewhere specified or included

Formula: C₁₂H₁₂Cl₂O₄

Color and Shape: Off-White Powder

Molecular weight: 290.01126

Ref: 45-1256015

Acetic acid, 2-[2,3-dichloro-4-(1-oxobutyl)phenoxy]-

CAS: 1217-67-0

Formula: C₁₂H₁₂Cl₂O₄

Color and Shape: Solid

Molecular weight: 291.1273

Ref: IN-DA0015MG

Ethacrynic Acid USP Related Compound A

CAS: 1217-67-0

Formula: C₁₂H₁₂Cl₂O₄

Color and Shape: White To Off-White Solid

Molecular weight: 291.12

Ref: 4Z-E-294

(2,3-Dichloro-4-butyrylphenoxy)acetic Acid

Controlled Product

CAS: 1217-67-0

Applications (2,3-Dichloro-4-butyrylphenoxy)acetic Acid is a impurity of Ethacrynic acid (E676000), which is a diuretic used to treat high blood pressure and swelling caused by congestive heart failure, liver failure and kidney failure. (2,3-Dichloro-4-butyrylphenoxy)acetic Acid is also used pharmaceutically and in agriculture.
References Beyer, et al.: J. Pharmacol. Exp. Ther., 147, 1 (1965); Kim., et al.: Am. J. Cardiol., 27, 407 (1971); Williamson, H.E., et al.: J. Clin. Pharmacol., 17, 663 (1977); Sumitomo Chemical Co.,Ltd.,Fr., FR 2066716 A5 19710806 (1971)

Formula: C₁₂H₁₂Cl₂O₄

Color and Shape: Neat

Molecular weight: 291.13

Ref: TR-D434935

Ethacrynic Acid EP Impurity A

CAS: 1217-67-0

Formula: C₁₂H₁₂Cl₂O₄

Molecular weight: 291.13

Ref: ST-EA-CP-E19001

(2,3-Dichloro-4-butyrylphenoxy)acetic Acid-d7

Controlled Product

CAS: 1217-67-0

Formula: C₁₂D₅H₇Cl₂O₄

Color and Shape: Neat

Molecular weight: 296.158

Ref: TR-D434937