CAS 1217510-38-7

Itraconazole-d5

CAS: 1217510-38-7

Formula: C₃₅H₃₃D₅Cl₂N₈O₄

Molecular weight: 710.67

Ref: 4Z-I-033

Itraconazole Impurity 5

CAS: 1217510-38-7, 84625-61-6

Formula: C₃₄H₃₅Cl₂N₈O₄·Cl

Color and Shape: Yellow Solid

Molecular weight: 690.61 35.45

Ref: 4Z-I-0331

Itraconazole-d5 (major)

Controlled Product

CAS: 1217510-38-7

Applications An isotopically labelled, orally active antimycotic structurally related to Ketoconazole.A representative lot was 88% d5, 12% d4 with no d0. It is a COVID19-related research product.
References Espinel-Ingroff, A., et al.: Antimicrob. Agents Chemother., 26, 5 (1984), Heykants, J., et al.: Mycoses, 32, Suppl 1, 67 (1989), Sugar, A.M., et al.: Curr. Clin. Top. Infect. Dis., 13, 74 (1993),

Formula: C₃₅₂H₅H₃₃Cl₂N₈O₄

Color and Shape: Neat

Molecular weight: 710.66

Ref: TR-I937502

Itraconazole-d5 (major)

CAS: 1217510-38-7

Itraconazole-d5 is a fluorescent derivative of itraconazole that is used for the detection of eosinophil cationic protein in the diagnosis of asthma. It binds to wild-type strains and inhibits fungal enzyme activities, such as concentration–time curves and minimal toxicity. The hydrogen bonding interactions between itraconazole-d5 and its target molecule are stronger than those between itraconazole and its target molecule. Itraconazole-d5 has been shown to inhibit the production of cationic proteins by inhibiting the activity of enzymes, such as polymerase chain reaction (PCR) and reverse transcriptase (RT), which are required for DNA synthesis.

Formula: C₃₅H₃₈Cl₂N₈O₄

Purity: Min. 95%

Molecular weight: 710.7 g/mol

Ref: 3D-SYB51038