CAS 1217619-62-9

(R)-nitro-Blebbistatin

CAS: 1217619-62-9

(R)-nitro-Blebbistatin is a stable, light-resistant variant of blebbistatin, avoiding cytotoxic breakdown during live cell imaging.

Formula: C₁₇H₁₃N₃O₄

Color and Shape: Solid

Molecular weight: 323.3

Ref: TM-T35458

R-(−)-7-Desmethyl-8-nitro blebbistatin

CAS: 1217619-62-9

R-(-)-7-Desmethyl-8-nitro blebbistatin is a drug product that has been custom synthesized for research and development purposes. The purity of this product is high, and the analytical data can be provided upon request. This compound is metabolized in vivo by a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. R-(-)-7-Desmethyl-8-nitro blebbistatin also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.

Formula: C₁₇H₁₃N₃O₄

Purity: Min. 95%

Molecular weight: 323.3 g/mol

Ref: 3D-SYB61962