
CAS 1217630-52-8
:2-DEMETHYLCOLCHICINE-D3
Description:
2-Demethylcolchicine-D3 is a synthetic derivative of colchicine, a well-known alkaloid derived from the plant Colchicum autumnale. This compound is characterized by its structural modifications that include the removal of a methyl group from the colchicine molecule, which alters its pharmacological properties. The "D3" designation indicates that this compound is labeled with three deuterium atoms, making it useful in various research applications, particularly in studies involving metabolic pathways and drug interactions. 2-Demethylcolchicine-D3 retains the core features of colchicine, such as its ability to inhibit microtubule polymerization, which is significant in cancer research and the study of inflammatory diseases. Its unique isotopic labeling allows for enhanced tracking in biological systems, providing insights into its mechanism of action and pharmacokinetics. As with many chemical substances, safety and handling precautions should be observed, and its use should be confined to controlled laboratory settings.
Formula:C21H23NO6
Synonyms:- NSC 180533-d3
- N-[(7S)-5,6,7,9-Tetrahydro-2-hydroxy-1,3,10-triMethoxy-9-oxobenzo[a]heptalen-7-yl]acetaMide-d3
- O2-DeMethylcolchicine-d3
- 2-DEMETHYLCOLCHICINE-D3
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