CAS 1217706-96-1

Ketoconazole-d8

Controlled Product

CAS: 1217706-96-1

Applications Deuterated Ketoconazole, an inhibitor of cytochrome P-450 dependent steps in the biosynthesis of steroid hormones in vivo. Antimetastatic and antineoplastic activity. Orally active 5-lipoxygenase and thromboxane synthase inhibitor.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Lambert, A., et al.: Biochem. Pharmacol., 35, 3999 (1986), Van Wauwe, J.P. and Janssen, P.A.J., J. Med. Chem., 32, 2231 (1989), Nardone, P.A., et al.: . Surg. Res., 44, 425 (1988), Tucker, W.F.G., et al.: Br. Med. J., 293, 882 (1986)

Formula: C₂₆H₂₀D₈Cl₂N₄O₄

Color and Shape: White To Beige

Molecular weight: 539.48

Ref: TR-K186002

Ketoconazole-d8

CAS: 1217706-96-1

Ketoconazole-d8 is an analog of ketoconazole, a medication used to treat fungal infections. This compound has been shown to have anticancer properties by inhibiting cyclin-dependent kinases (CDKs) and inducing apoptosis in cancer cells. Ketoconazole-d8 has been found to be effective against a variety of human cancer cell lines, including those resistant to other kinase inhibitors such as linezolid. This compound also inhibits the activity of certain proteins involved in tumor growth and development. Ketoconazole-d8 is commonly used in research studies to investigate the mechanisms behind its anticancer effects. It can be detected in urine samples using mass spectrometry techniques, making it a useful tool for pharmacokinetic studies.

Formula: C₂₆H₂₈Cl₂N₄O₄

Purity: Min. 95%

Molecular weight: 539.5 g/mol

Ref: 3D-SYB70696