CAS 1217723-41-5

2,2-dichloro-N-[(2S,3S)-1,1,2-trideuterio-1,3-dihydroxy-3-(4-methylsulfonylphenyl)propan-2-yl]acetamide

Description:

2,2-Dichloro-N-[(2S,3S)-1,1,2-trideuterio-1,3-dihydroxy-3-(4-methylsulfonylphenyl)propan-2-yl]acetamide is a complex organic compound characterized by its specific structural features, including dichloro and deuterated groups. The presence of two chlorine atoms indicates a high degree of reactivity, particularly in nucleophilic substitution reactions. The deuterium labeling suggests applications in isotopic studies or tracing mechanisms in biochemical pathways. The compound contains a sulfonyl group, which enhances its solubility and potential interactions with biological systems. The stereochemistry, indicated by the (2S,3S) configuration, suggests that the compound may exhibit specific biological activity or selectivity due to its three-dimensional arrangement. Additionally, the presence of hydroxyl groups contributes to its polarity and potential hydrogen bonding capabilities, which can influence its pharmacokinetic properties. Overall, this compound's unique characteristics make it of interest in medicinal chemistry and research applications, particularly in the development of therapeutic agents or as a tool in biochemical studies.

Formula: C₁₂H₁₂Cl₂D₃NO₅S

InChI: InChI=1/C12H15Cl2NO5S/c1-21(19,20)8-4-2-7(3-5-8)10(17)9(6-16)15-12(18)11(13)14/h2-5,9-11,16-17H,6H2,1H3,(H,15,18)/t9-,10-/s2/i6D2,9D

InChI key: InChIKey=OTVAEFIXJLOWRX-CZECYKEONA-N

SMILES: [C@@H]([C@](NC(C(Cl)Cl)=O)(C(O)([2H])[2H])[2H])(O)C1=CC=C(S(C)(=O)=O)C=C1

Synonyms:

• 2,2-dichloro-N-[(2S,3S)-1,1,2-trideuterio-1,3-dihydroxy-3-(4-methylsulfonylphenyl)propan-2-yl]acetamide
• [2H3]-ent-Thiamphenicol

ent-Thiamphenicol-d3

CAS: 1217723-41-5

Formula: C₁₂H₁₂D₃Cl₂NO₅S

Molecular weight: 359.23

Ref: 4Z-T-6118

ent-Thiamphenicol-d3

Controlled Product

CAS: 1217723-41-5

Applications The labelled enatiomeric analogue of the antimicrobial agent Thiamphenicol (T344160).
References Gal, J. et al.: J. Pharmac. Sci., 77, 1062 (1988); Martin, J. et al.: Anal. Biochem., 96, 215 (1979);

Formula: C₁₂H₁₂D₃Cl₂NO₅S

Color and Shape: White To Off-White

Molecular weight: 359.24

Ref: TR-T344212