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CAS 1217724-28-1

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N-FMoc-3-hydroxy-D-phenylalanine

Description:
N-FMoc-3-hydroxy-D-phenylalanine is a derivative of the amino acid phenylalanine, modified with a 9-fluorenylmethoxycarbonyl (FMoc) protecting group at the nitrogen atom. This compound is characterized by its chiral center, which contributes to its specific stereochemistry as a D-enantiomer. The presence of a hydroxy group at the 3-position of the phenyl ring enhances its solubility and reactivity, making it useful in peptide synthesis and medicinal chemistry. The FMoc group serves as a protective moiety that can be removed under mild basic conditions, allowing for selective deprotection during peptide assembly. This compound is often utilized in the synthesis of peptides and proteins, particularly in the context of solid-phase peptide synthesis (SPPS). Its unique structural features contribute to its role in research and development, particularly in the design of bioactive compounds and pharmaceuticals. As with many amino acid derivatives, it is important to handle N-FMoc-3-hydroxy-D-phenylalanine with care, following appropriate safety protocols.
Formula:C24H21NO5
Synonyms:
  • N-Fmoc-D-3-hydroxy-Phenylalanine
  • (2R)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-(3-hydroxyphenyl)propanoic acid
  • N-α-(9-Fluorenylmethoxycarbonyl)-3-hydroxy-D-phenylalanine
  • N-FMoc-3-hydroxy-D-phenylalanine
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