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CAS 1217733-09-9

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(S)-Citalopram-d6 Oxalate

Description:
(S)-Citalopram-d6 oxalate is a deuterated form of the selective serotonin reuptake inhibitor (SSRI) citalopram, which is primarily used in the treatment of depression and anxiety disorders. The "d6" designation indicates that this compound contains six deuterium atoms, which are isotopes of hydrogen, replacing the regular hydrogen atoms in the citalopram structure. This modification enhances the compound's stability and allows for more precise tracking in pharmacokinetic studies and metabolic research. The oxalate salt form is used to improve the solubility and bioavailability of the drug. As a chiral molecule, (S)-Citalopram-d6 exhibits specific stereochemical properties, with the (S) configuration being the therapeutically active enantiomer. Its mechanism of action involves the inhibition of serotonin reuptake in the brain, leading to increased serotonin levels and improved mood. The compound is primarily utilized in research settings, particularly in studies involving drug metabolism and pharmacodynamics, due to its labeled nature.
Formula:C22H23FN2O5
Synonyms:
  • [2H6]- (S)-Citalopram Oxalate
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  • (S)-Citalopram-d6 Oxalate

    Controlled Product
    CAS:
    <p>Stability Hygroscopic<br>Applications A labelled inhibitor of serotonin (5-HT) uptake. Antidepressant.<br>References Christensen, A.V., et al.: Eur. J. Pharmacol., 41, 153 (1977), Keller, M.B., et al.: J. Clin. Psychiatry, 61, 896 (2000), Von Moltke, L.L., et al.: Drug Metab. Dispos., 29, 1102 (2001), Fish, E.W., et al.: J. Pharmacol. Exp. Ther, 308, 474 (2004),<br></p>
    Formula:C202H6H15FN2O·C2H2O4
    Color and Shape:White To Off-White
    Molecular weight:420.46

    Ref: TR-C505012

    1mg
    484.00€
    10mg
    3,241.00€