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CAS 1217769-79-3

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(S)-Casodex-d4

Description:
(S)-Casodex-d4, also known by its chemical name, is a deuterated form of the non-steroidal anti-androgen drug bicalutamide, which is primarily used in the treatment of prostate cancer. The "d4" designation indicates that this compound contains four deuterium atoms, which are isotopes of hydrogen, replacing the regular hydrogen atoms in the molecular structure. This modification can enhance the stability and metabolic profile of the compound, making it useful in pharmacokinetic studies. The characteristics of (S)-Casodex-d4 include its ability to selectively bind to androgen receptors, thereby inhibiting the action of androgens like testosterone. This action helps to slow down or stop the growth of prostate cancer cells that rely on androgens for proliferation. The compound is typically administered orally and is known for its relatively long half-life, allowing for once-daily dosing. As a research chemical, (S)-Casodex-d4 is valuable in studies investigating drug metabolism and the pharmacodynamics of anti-androgen therapies.
Formula:C18H14F4N2O4S
Synonyms:
  • (S)-Bicalutamide-d4
  • (S)-Casodex-d4
  • (2S)-N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl-d4)sulfonyl]-2-hydroxy-2-methylpropanamide
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Found 2 products.
  • (S)-Bicalutamide-D4
    TRC
    + Info

    (S)-Bicalutamide-D4

    Controlled Product
    CAS:
    Formula:C18D4H10F4N2O4S
    Color and Shape:Neat
    Molecular weight:434.398

    Ref: TR-B382012

    2500µg
    10,511.00€
  • (S)-Bicalutamide-d4
    Biosynth
    + Info

    (S)-Bicalutamide-d4

    CAS:
    <p>(S)-Bicalutamide-d4 is a potent inhibitor of androgen receptor signaling that is used in the treatment of prostate cancer. It is an analog of bicalutamide, which is a non-steroidal anti-androgen drug that blocks the action of testosterone on cancer cells. (S)-Bicalutamide-d4 has been shown to induce apoptosis in human prostate cancer cell lines and inhibit tumor growth in animal models. It also has inhibitory effects on hyaluronan synthesis and kinase activity, which may contribute to its anti-cancer properties. (S)-Bicalutamide-d4 has been used as a tracer in studies of somatostatin receptors in Chinese hamster ovary cells and urine samples from prostate cancer patients treated with octreotide inhibitors. Its stable isotopic labeling makes it useful for pharmacokinetic studies and metabolic profiling.</p>
    Formula:C18H14F4N2O4S
    Purity:Min. 95%
    Molecular weight:434.4 g/mol

    Ref: 3D-SYB76979

    1mg
    2,804.00€