CAS 1217782-44-9

7,8-Dihydro-L-Biopterin-d3

Controlled Product

CAS: 1217782-44-9

Applications The labelled reduced form of Biopterin. An oxidation product of tetrahydrobiopterin, a naturally occurring cofactor of the aromatic amino acid hydroxylase and is involved in the synthesis of tyrosine and the neurotransmitters dopamine and serotonin. It is a noncompetitive inhibitor of GTP cyclohydrolase I, with a Ki of 14.4 µM.
References Shen, R., et al.: Biochim Biophys Acta., 965, 9 (1988), Kwon, N.S., et al.: J. Biol. Chem., 264, 20498 (1989), Werner, E.R., et al.: Proc. Soc. Exp. Biol. Med., 203, 1 (1993),

Formula: C₉H₁₀D₃N₅O₃

Color and Shape: Neat

Molecular weight: 242.25

Ref: TR-D448552