CAS 1217837-17-6

5-Iodo-A-85380 (dihydrochloride)

CAS: 1217837-17-6

5-Iodo-A-85380 (dihydrochloride)

Purity: 98%

Molecular weight: 363.02g/mol

Ref: 54-OR1035896

5-IODO-A-85380 Dihydrochloride

Controlled Product

CAS: 1217837-17-6

Applications 5-IODO-A-85380 Dihydrochloride is a highly potent and subtype-selective agonist for AChR α4β2 and AChR α6β2.
References Koren, A.O., et al.: J. Med. Chem., 41, 3690-3698 (1998); Muhkin, A.G., et al.: Mol. Pharmacol., 57, 642-649 (2000); Mogg, A.J., et al.: Neuropharmacology, 47, 848-859 (2004);

Formula: C₉H₁₁IN₂O·2HCl

Color and Shape: Neat

Molecular weight: 363.02

Ref: TR-I737008

(S)-3-(Azetidin-2-ylmethoxy)-5-iodopyridine dihydrochloride

CAS: 1217837-17-6

5-Iodo-A-85380 dihydrochloride is an acetylcholine antagonist that blocks nicotinic acetylcholine receptors. It is used to study the function of acetylcholine and cholinergic synapses in animals. 5-Iodo-A-85380 dihydrochloride is also used to study the effects of drugs on αβ nicotinic receptors and glutamate receptors. This drug binds to extracellular Ca2+, which reduces its effect on these receptors. It has been shown to decrease synaptic activity in rats, with a dose dependent response. 5-Iodo-A-85380 dihydrochloride has an inhibitory effect on fluorimetric assays for glutamate and amino acids, indicating that it may be useful in studies of neurotransmitter release.

Formula: C₉H₁₁IN₂O·2HCl

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 363.03 g/mol

Ref: 3D-SYB83717

5-Iodo-A-85380 dihydrochloride

CAS: 1217837-17-6

α4β2 and α6β2 nicotinic acetylcholine receptors agonist

Formula: C₉H₁₃Cl₂IN₂O

Purity: 98%

Color and Shape: Solid

Molecular weight: 363.02

Ref: TM-T22521