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CAS 1217840-61-3

:

Fmoc-N-Me-His(Trt)-OH

Description:
Fmoc-N-Me-His(Trt)-OH, with the CAS number 1217840-61-3, is a protected derivative of histidine, an amino acid commonly found in proteins. The "Fmoc" (9-fluorenylmethoxycarbonyl) group serves as a protective group for the amino functionality, allowing for selective reactions during peptide synthesis. The "N-Me" indicates that the nitrogen atom in the side chain is methylated, which can influence the compound's steric and electronic properties. The "His" refers to histidine, which contains an imidazole side chain that can participate in various biochemical interactions, including metal ion coordination and proton transfer. The "Trt" (trityl) group protects the side chain of histidine, providing stability and preventing unwanted reactions during synthesis. This compound is typically used in peptide synthesis and research applications, particularly in the development of peptide-based drugs and bioconjugates. Its characteristics, including solubility and reactivity, are influenced by the protective groups, making it a versatile building block in organic and medicinal chemistry.
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