N-DesMethyl Selegiline-D5, also known as DesMethyl deprenyl-D5, is a deuterated analog of the drug selegiline, which is primarily used in the treatment of Parkinson's disease and major depressive disorder. This compound is characterized by the presence of deuterium, a stable isotope of hydrogen, which enhances its stability and alters its pharmacokinetic properties. The incorporation of deuterium can improve the metabolic profile of the drug, potentially leading to a longer half-life and reduced side effects. N-DesMethyl Selegiline-D5 functions as a selective monoamine oxidase B (MAO-B) inhibitor, which helps increase the levels of dopamine in the brain, thereby alleviating symptoms associated with dopamine deficiency. Its chemical structure includes a phenethylamine backbone, and the presence of deuterium allows for advanced analytical techniques, such as mass spectrometry, to trace its metabolic pathways. As a research chemical, it is primarily used in studies related to neuropharmacology and the development of therapeutic agents targeting neurodegenerative diseases.

N-DesMethyl Selegiline-D5/ DesMethyl deprenyl-D5

1217977-04-2: N-DesMethyl Selegiline-D5, also known as DesMethyl deprenyl-D5, is a deuterated analog of the drug selegiline, which is primarily used in the treatment of Parkinson's disease and major depressive disorder. This compound is characterized by the presence of deuterium, a stable isotope of hydrogen, which enhances its stability and alters its pharmacokinetic properties. The incorporation of deuterium can improve the metabolic profile of the drug, potentially leading to a longer half-life and reduced side effects. N-DesMethyl Selegiline-D5 functions as a selective monoamine oxidase B (MAO-B) inhibitor, which helps increase the levels of dopamine in the brain, thereby alleviating symptoms associated with dopamine deficiency. Its chemical structure includes a phenethylamine backbone, and the presence of deuterium allows for advanced analytical techniques, such as mass spectrometry, to trace its metabolic pathways. As a research chemical, it is primarily used in studies related to neuropharmacology and the development of therapeutic agents targeting neurodegenerative diseases.

<p>Applications A labelled metabolite of Deprenyl (D288641) (Selegiline).<br>References Dyck, L., et al.: Drug Metab. Dispos., 29, 1156 (2001), Damaj, M., et al.: J. Pharmacol. Exp. Ther., 320, 250 (2007),<br></p>

CAS 1217977-04-2

N-DesMethyl Selegiline-D5/ DesMethyl deprenyl-D5

R-(-)-N-Demethyl Deprenyl-d5

Ref: TR-D230922