CAS 1218-24-2

5′-Chloro-2′-hydroxychalcone

Description:

5′-Chloro-2′-hydroxychalcone, with the CAS number 1218-24-2, is a synthetic organic compound belonging to the chalcone class, which are characterized by a structure comprising two aromatic rings connected by a three-carbon α,β-unsaturated carbonyl system. This specific compound features a chlorine atom at the 5′ position and a hydroxyl group at the 2′ position of the chalcone structure, which can influence its chemical reactivity and biological activity. It is typically a yellow to orange solid, exhibiting moderate solubility in organic solvents. The presence of the hydroxyl group may enhance its potential for hydrogen bonding, while the chlorine substituent can affect its electronic properties and lipophilicity. 5′-Chloro-2′-hydroxychalcone has garnered interest in various fields, including medicinal chemistry, due to its potential antioxidant, anti-inflammatory, and anticancer properties. Its reactivity can also make it a useful intermediate in organic synthesis, particularly in the development of more complex molecules.

Formula: C₁₅H₁₁ClO₂

InChI: InChI=1S/C15H11ClO2/c16-12-7-9-15(18)13(10-12)14(17)8-6-11-4-2-1-3-5-11/h1-10,18H

InChI key: InChIKey=GVKYSLWFMZCXBQ-UHFFFAOYSA-N

SMILES: C(C=CC1=CC=CC=C1)(=O)C2=C(O)C=CC(Cl)=C2

Synonyms:

• 1-(5-Chloro-2-hydroxyphenyl)-3-phenyl-2-propen-1-one
• 2-Propen-1-one, 1-(5-chloro-2-hydroxyphenyl)-3-phenyl-
• 2′-Hydroxy-5′-chlorochalcone
• Chalcone, 5′-chloro-2′-hydroxy-
• 5′-Chloro-2′-hydroxychalcone