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CAS 1218-35-5

:

Xylometazoline hydrochloride

Description:
Xylometazoline hydrochloride is a sympathomimetic agent primarily used as a topical decongestant. It is commonly found in nasal sprays and drops, providing relief from nasal congestion associated with conditions such as colds, allergies, and sinusitis. The compound works by stimulating alpha-adrenergic receptors in the nasal mucosa, leading to vasoconstriction and reduced swelling of the blood vessels, which alleviates congestion. Xylometazoline hydrochloride is typically a white to off-white crystalline powder, soluble in water, and has a relatively low molecular weight. Its pharmacological effects usually manifest within minutes and can last for several hours, making it effective for short-term use. However, prolonged use can lead to rebound congestion, a condition known as rhinitis medicamentosa. As with any medication, it is important to follow dosing guidelines to minimize potential side effects, which may include local irritation or dryness of the nasal mucosa. Overall, xylometazoline hydrochloride is a widely used and effective agent for managing nasal congestion.
Formula:C16H24N2·ClH
InChI:InChI=1S/C16H24N2.ClH/c1-11-8-13(16(3,4)5)9-12(2)14(11)10-15-17-6-7-18-15;/h8-9H,6-7,10H2,1-5H3,(H,17,18);1H
InChI key:InChIKey=YGWFCQYETHJKNX-UHFFFAOYSA-N
SMILES:C(C1=C(C)C=C(C(C)(C)C)C=C1C)C=2NCCN2.Cl
Synonyms:
  • 1H-Imidazole, 2-[[4-(1,1-dimethylethyl)-2,6-dimethylphenyl]methyl]-4,5-dihydro-, hydrochloride (1:1)
  • 1H-Imidazole, 2-[[4-(1,1-dimethylethyl)-2,6-dimethylphenyl]methyl]-4,5-dihydro-, monohydrochloride
  • 2-(4-Tert-Butyl-2,6-Dimethylbenzyl)-2-Imidazoline Hydrochloride
  • 2-(4-Tert-Butyl-2,6-Dimethylbenzyl)-2-Imidazolinmonohydrochloride
  • 2-(4-tert-butyl-2,6-dimethylbenzyl)-4,5-dihydro-1H-imidazol-1-ium chloride
  • 2-Imidazoline, 2-(4-tert-butyl-2,6-dimethylbenzyl)-, monohydrochloride
  • 2-[[4-(1,1-Dimethylethyl)-2,6-Dimethylphenyl]Methyl]-4,5-Dihydro-1H-Imidazol
  • Blox 4
  • Brizolin
  • Galazolin
  • See more synonyms
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