CAS 1218-40-2

5-Methoxy-N,N-diethyltryptamine

Description:

5-Methoxy-N,N-diethyltryptamine (commonly referred to as 5-MeO-DET) is a synthetic compound belonging to the tryptamine class, which is characterized by its structural similarity to the neurotransmitter serotonin. This substance features a methoxy group at the 5-position of the indole ring and two ethyl groups attached to the nitrogen atom of the amine side chain. 5-MeO-DET is known for its psychoactive properties, often explored in the context of entheogenic and psychedelic experiences. It is typically administered in various forms, including oral ingestion or vaporization. The compound is not widely studied in clinical settings, and its pharmacological profile includes interactions with serotonin receptors, particularly the 5-HT2A receptor, which is implicated in the modulation of mood and perception. As with many psychoactive substances, the effects can vary significantly among individuals, and the compound may carry risks of adverse reactions or psychological distress. Due to its psychoactive nature, 5-MeO-DET is subject to legal restrictions in some jurisdictions.

Formula: C₁₅H₂₂N₂O

InChI: InChI=1S/C15H22N2O/c1-4-17(5-2)9-8-12-11-16-15-7-6-13(18-3)10-14(12)15/h6-7,10-11,16H,4-5,8-9H2,1-3H3

InChI key: InChIKey=KGDVJQQWCDDEPP-UHFFFAOYSA-N

SMILES: C(CN(CC)CC)C=1C=2C(NC1)=CC=C(OC)C2

Synonyms:

• N,N-Diethyl-5-methoxy-1H-indole-3-ethanamine
• 5-Methoxy-N,N-diethyltryptamine
• 1H-Indole-3-ethanamine, N,N-diethyl-5-methoxy-
• Indole, 3-[2-(diethylamino)ethyl]-5-methoxy-

5-methoxy DET

CAS: 1218-40-2

Formula: C₁₅H₂₂N₂O

Molecular weight: 246.348

Ref: IN-DA001625

N,N-diethyl-2-(5-methoxy-1H-indol-3-yl)ethan-1-amine

Controlled Product

CAS: 1218-40-2

Formula: C₁₅H₂₂N₂O

Color and Shape: Neat

Molecular weight: 246.40

Ref: TR-M262225

5-Methoxy det

Controlled Product

CAS: 1218-40-2

5-Methoxy det is a low potency 5-HT2A receptor agonist, with an affinity for the 5-HT1A receptor. It has been shown to be a serotonin uptake inhibitor and to activate serotonergic neurons. 5-Methoxy det has also been shown to have functional activity at both 5-HT2A and 5-HT1A receptors. The compound is metabolized by cytochrome P450 enzymes (CYP2D6) and has pharmacokinetic properties similar to other drugs in this class.

Formula: C₁₅H₂₂N₂O

Purity: Min. 95%

Molecular weight: 246.35 g/mol

Ref: 3D-BAA21840

5-methoxy DET

CAS: 1218-40-2

5-Methoxy DET, a synthetic tryptamine designer drug, structurally resembles the potent hallucinogen N,N-DMT. It inhibits serotonin uptake (IC50 of 2.4 µM) and activates 5-HT2A receptors (EC50 of 8.11 nM). This compound is designed for forensic and research applications.

Formula: C₁₅H₂₂N₂O

Color and Shape: Solid

Molecular weight: 246.354

Ref: TM-T84410