CAS 121808-62-6

Pidotimod

Description:

Pidotimod is a synthetic immunomodulatory agent primarily used in the treatment of recurrent respiratory infections, particularly in children. It is characterized by its ability to enhance the immune response, particularly by stimulating the activity of T lymphocytes and promoting the production of cytokines. Pidotimod is known for its low toxicity and favorable safety profile, making it suitable for long-term use. The substance is typically administered orally and is well-absorbed in the gastrointestinal tract. Its mechanism of action involves modulating both innate and adaptive immunity, which helps in improving the body's defense against pathogens. Pidotimod has also been studied for its potential benefits in various allergic and autoimmune conditions. As a chemical entity, it is classified as a small molecule with a specific molecular structure that contributes to its biological activity. Overall, pidotimod represents a valuable therapeutic option in enhancing immune function and reducing the frequency of infections.

Formula: C₉H₁₂N₂O₄S

InChI: InChI=1S/C9H12N2O4S/c12-7-2-1-5(10-7)8(13)11-4-16-3-6(11)9(14)15/h5-6H,1-4H2,(H,10,12)(H,14,15)/t5-,6-/m0/s1

InChI key: InChIKey=UUTKICFRNVKFRG-WDSKDSINSA-N

SMILES: C(=O)(N1[C@H](C(O)=O)CSC1)[C@H]2NC(=O)CC2

Synonyms:

• (4R)-3-[[(2S)-5-Oxo-2-pyrrolidinyl]carbonyl]-4-Thiazolidinecarboxylic acid
• 4-Thiazolidinecarboxylic acid, 3-[(5-oxo-2-pyrrolidinyl)carbonyl]-, [R-(R*,S*)]-
• 4-Thiazolidinecarboxylic acid, 3-[[(2S)-5-oxo-2-pyrrolidinyl]carbonyl]-, (4R)-
• Adimod
• Axil (pharmaceutical)
• Onaka
• Pidotimond
• Pigitil
• Polimod
• Pidotimod

(4R)-3-{[(2S)-5-oxopyrrolidin-2-yl]carbonyl}-1,3-thiazolidine-4-carboxylic acid

CAS: 121808-62-6

Formula: C₉H₁₂N₂O₄S

Purity: 98%

Color and Shape: Solid

Molecular weight: 244.2676

Ref: IN-DA00162L

Pidotimod

CAS: 121808-62-6

Pidotimod is a synthetic dipeptide with immunomodulatory properties.

Formula: C₉H₁₂N₂O₄S

Purity: 97.56% - 99.74%

Color and Shape: Almost White To White Crystalline Powder

Molecular weight: 244.27

Ref: TM-T1532

Pidotimod

CAS: 121808-62-6

Pidotimod

Purity: ≥95%

Molecular weight: 244.27g/mol

Ref: 54-BUP16766

Pidotimod

CAS: 121808-62-6

Formula: C₉H₁₂N₂O₄S

Color and Shape: White To Off-White Solid

Molecular weight: 244.27

Ref: 4Z-P-136001

(R)-3-((S)-5-Oxopyrrolidine-2-Carbonyl)Thiazolidine-4-Carboxylic Acid

CAS: 121808-62-6

(R)-3-((S)-5-Oxopyrrolidine-2-Carbonyl)Thiazolidine-4-Carboxylic Acid

Purity: 98%

Molecular weight: 244.27g/mol

Ref: 54-OR1008478

Pidotimod

CAS: 121808-62-6

Formula: C₉H₁₂N₂O₄S

Molecular weight: 244.27

Ref: 7W-GP9654

Pidotimod

CAS: 121808-62-6

Formula: C₉H₁₂N₂O₄S

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 244.27

Ref: 3B-P2147

Pidotimod

Controlled Product

CAS: 121808-62-6

Applications Immunostimulant used in patients with cell-mediated immunodepression.
References Gu, C., et al.: Pharm. Res., 25, 979 (2008), Fliri, A., et al.: J. Med. Chem., 52, 8038 (2009), Giagulli, C., et al.: Int. Immunopharmacol., 9, 1366 (2009),

Formula: C₉H₁₂N₂O₄S

Color and Shape: Neat

Molecular weight: 244.27

Ref: TR-P437650

Pidotimod

CAS: 121808-62-6

Pidotimod is a small molecule (dipeptide) that acts as immunomodulator. It activates the immune system by binding to Toll-like receptor (TLR) 4 and TLR2 and it is involved in the regulation of TLRs signaling pathways. Pidotimod has chemokine activity on CXC chemokine receptor 3 (CXCR3) that triggers monocyte adhesion and migration by activation of tyrosine phosphorylation-based cell signaling. Recent studies showed that pidotimod can be used to treat acute respiratory tract infections (RTIs) and its pharmacokinetic studies has shown its ability to boost the immunoresponse and favouring the increase in the level of immunoglobulins (IgA, IgM, IgG) and T-lymphocytes (CD3+, CD4+). Pidotimod also exhibits anti-inflammatory properties by inhibiting the production of pro-inflammatory molecules such as IL-6 and TNF-α, which are linked to autoimmune diseases

Formula: C₉H₁₂N₂O₄S

Purity: Min 98%

Color and Shape: White Powder

Molecular weight: 244.27 g/mol

Ref: 3D-FP27040

Pidotimod - Bio-X ™

CAS: 121808-62-6

Pidotimod is a small molecule (dipeptide) that acts as immunomodulator. It activates the immune system by binding to Toll-like receptor (TLR) 4 and TLR2 and it is involved in the regulation of TLRs signaling pathways. Pidotimod has chemokine activity on CXC chemokine receptor 3 (CXCR3) that triggers monocyte adhesion and migration by activation of tyrosine phosphorylation-based cell signaling. Recent studies showed that pidotimod can be used to treat acute respiratory tract infections (RTIs) and its pharmacokinetic studies has shown its ability to boost the immunoresponse and favouring the increase in the level of immunoglobulins (IgA, IgM, IgG) and T-lymphocytes (CD3+, CD4+). Pidotimod also exhibits anti-inflammatory properties by inhibiting the production of pro-inflammatory molecules such as IL-6 and TNF-α, which are linked to autoimmune diseases.

Formula: C₉H₁₂N₂O₄S

Color and Shape: Powder

Molecular weight: 244.27 g/mol

Ref: 3D-BP164260

(R)-3-((S)-5-Oxopyrrolidine-2-carbonyl)thiazolidine-4-carboxylic acid

CAS: 121808-62-6

Formula: C₉H₁₂N₂O₄S

Purity: 98%

Color and Shape: Solid

Molecular weight: 244.27

Ref: 10-F211857